Diseases of the endocrine system and metabolic disorders (endocrinology)

Empty saddle syndrome.

The phrase "empty sella turcica" (EST) entered medical practice in 1951. After anatomical work, it was proposed by S. Busch, who studied the autopsy material of 788 people who died from diseases not associated with pituitary pathology.

Causes and pathogenesis of panhypopituitarism

Hormonal deficiency of the hypothalamic-adenohypophyseal system develops due to infectious, toxic, vascular (for example, in systemic collagen diseases), traumatic, tumor and allergic (autoimmune) lesions of the anterior pituitary gland and/or hypothalamus.

Panhypopituitarism - Information Review

This concept includes hypothalamic-pituitary insufficiency, postpartum hypopituitarism - Sheehan's syndrome, pituitary cachexia - Simmonds' disease. In 1974, M. Simmonds described postpartum, septic-embolic necrosis of the anterior pituitary gland with a fatal outcome in a state of severe cachexia and catastrophically developed senile involution of organs and tissues.

Non-diabetes mellitus

Diabetes insipidus is a disease characterized by diabetic exhaustion, increased plasma osmolarity, which stimulates the thirst mechanism, and compensatory consumption of large amounts of fluid.

Syndrome of inadequate vasopressin production

Excessive production of vasopressin can be adequate, i.e. arise as a result of the physiological reaction of the posterior pituitary gland in response to appropriate stimuli (blood loss, taking diuretics, hypovolemia, hypotension, etc.), and inadequate.

Treatment of persistent galactorrhea-amenorrhea syndrome

Drug therapy occupies a major place in the treatment of all forms of persistent galactorrhea-amenorrhea syndrome of hypothalamic-pituitary genesis. In case of adenomas, it is supplemented or competes with neurosurgical intervention or with remote radiation therapy.

Persistent galactorrhea-amenorrhea syndrome - Information review

Persistent galactorrhea-amenorrhea syndrome is a characteristic clinical symptom complex that develops in women due to a long-term increase in prolactin secretion. In rare cases, a similar symptom complex develops with a normal serum level of prolactin, which has an excessively high biological activity.

Nelson's syndrome

Nelson's syndrome is a disease characterized by chronic adrenal insufficiency, hyperpigmentation of the skin, mucous membranes and the presence of a pituitary tumor. It occurs after removal of the adrenal glands in Itsenko-Cushing's disease.

Treatment of Icenko-Cushing's disease

Pathogenetic and symptomatic methods are used to treat the disease. Pathogenetic methods are aimed at normalizing the pituitary-adrenal relationship, symptomatic methods are aimed at compensating for metabolic disorders.

What triggers Icenko-Cushing's disease?

The causes of the disease have not been established. In women, Itsenko-Cushing's disease most often occurs after childbirth. The anamnesis of patients of both sexes includes head injuries, concussion, skull injuries, encephalitis, arachnoiditis and other CNS lesions.