Diseases of the endocrine system and metabolic disorders (endocrinology)

Subacute de Quervain's thyroiditis.

De Quervain's subacute thyroiditis, or granulomatous thyroiditis, is one of the most common forms of the disease. An increase in the incidence of the disease is noted in the autumn-winter period. Women are ill 4 times more often than men, the age of patients may vary, but the greatest number of cases occurs at 30-40 years of age.

Non-pulmonary acute thyroiditis

Non-purulent acute thyroiditis occurs as an aseptic inflammation due to trauma and hemorrhage in the gland or after radiation therapy.

Acute purulent thyroiditis.

Acute purulent thyroiditis is caused by coccal flora and is rare. The use of antibiotics to treat coccal infections has made this form of thyroiditis very rare.

Thyroiditis

The term "thyroiditis" unites thyroid diseases that differ in etiology, pathogenesis, and an obligatory component of which is inflammation. With different pathogenesis, the diseases have clinically similar symptoms, which complicates differential diagnosis in some cases.

Causes and pathogenesis of hypothyroidism

In the vast majority of cases (90-95%), the disease is caused by a pathological process in the thyroid gland itself, which reduces the level of hormone production (primary hypothyroidism). Disruption of the regulatory and stimulating effect of pituitary thyrotropin or hypothalamic releasing factor (thyroliberin) leads to secondary hypothyroidism, which is significantly less common than primary hypothyroidism.

Hypothyroidism - Information Overview

Insufficient levels of thyroid hormones in organs and tissues lead to the development of hypothyroidism, a disease first described by W. Gall in 1873. The term “myxedema”, coined by V. M. Ord (1878), means only mucous swelling of the skin and subcutaneous tissue.

Treatment of diffuse toxic goiter

Currently, there are three main methods of treating diffuse toxic goiter: drug therapy, surgical intervention - subtotal resection of the thyroid gland, and treatment with radioactive iodine. All available methods of treating diffuse toxic goiter lead to a decrease in the elevated level of circulating thyroid hormones to normal values.

Symptoms of diffuse toxic goiter

The pathogenesis of clinical symptoms is due to the influence of excess thyroid hormones on various organs and systems of the body. The complexity and multiplicity of factors involved in the development of thyroid pathology also determine the diversity of clinical manifestations of the disease.

Causes of diffuse toxic goiter

Currently, diffuse toxic goiter (DTG) is considered an organ-specific autoimmune disease. Its hereditary nature is confirmed by the fact that there are familial cases of goiter, thyroid antibodies are detected in the blood of relatives of patients, and a high frequency of other autoimmune diseases among family members is noted.

Diffuse toxic goiter (basal goiter disease) - Information Overview

Diffuse toxic goiter (Graves' disease, Basedow's goiter, Graves' disease) is the most common thyroid disease, which occurs due to increased production of thyroid hormones.