In clinical practice, natural glucocorticoids are used - cortisone and hydrocortisone and their synthetic and semi-synthetic derivatives. Depending on the presence or absence of fluorine or chlorine ions in the structure of the drug, glucocorticoids are divided into non-halogenated (prednisone, prednisolone, methylprednisolone) and halogenated compounds (triamcinolone, dexamethasone and betamethasone).