Infectious and parasitic diseases

Yellow fever - Symptoms.

At the onset of the disease, yellow fever symptoms such as: hyperemia of the face, neck and upper body, pronounced injection of the scleral vessels, swelling of the eyelids, swelling of the lips, puffiness of the face ("amarilla mask") occur. Photophobia and lacrimation are characteristic.

Yellow fever - Causes and pathogenesis

Yellow fever is caused by the RNA-containing virus Viceronhilus tropicus of the genus Flavivirus of the family Flaviviridae, which belongs to the group of arboviruses. The capsid is spherical; its dimensions are about 40 nm.

Yellow Fever - Overview

Yellow fever is an acute natural focal transmissible viral disease characterized by liver damage, hemorrhagic syndrome, and a severe cyclical course.

Omsk hemorrhagic fever

Omsk hemorrhagic fever (OHF) is an acute viral zoonotic natural focal disease with a transmissible mechanism of pathogen transmission, characterized by undulating fever, general intoxication, development of hemorrhagic syndrome and vegetative-vascular dystonia, as well as damage to the central nervous system, lungs, kidneys and a relatively benign course.

Crimean hemorrhagic fever - Treatment

For specific treatment of Crimean hemorrhagic fever, hyperimmune specific equine γ-globulin was previously used. Currently, a certain experience of using ribavirin in patients with viral hemorrhagic fevers has been accumulated. In Stavropol Krai, a ribavirin treatment regimen for patients with Crimean hemorrhagic fever has been introduced into clinical practice in accordance with the recommendations of the US Centers for Disease Control and Prevention. It is preferable to prescribe the drug in the first 4 days from the onset of the disease (the period of maximum viremia).

Crimean hemorrhagic fever - Diagnosis

Crimean hemorrhagic fever is differentiated from other hemorrhagic fevers, influenza, leptospirosis, meningococcemia, typhoid fever, surgical diseases with the syndrome of "acute abdomen"; as well as from thrombocytopenic purpura (Werlhof's disease) with a characteristic subacute onset, lack of temperature reaction, hemorrhagic rash from small petechiae to large ecchymoses on the flexor surfaces of the limbs, trunk, frequent nosebleeds and other bleeding, hypochromic anemia, leukocytosis, thrombocytopenia and the absence of changes in the cardiovascular system.

Crimean hemorrhagic fever - Symptoms

The initial period lasts 3-4 days; symptoms of Crimean hemorrhagic fever appear such as: sudden rise in temperature, severe headache, aches and pains throughout the body (especially in the lower back), severe weakness, loss of appetite, nausea, and vomiting not associated with food intake.

Crimean hemorrhagic fever - Causes and pathogenesis

The cause of Crimean hemorrhagic fever is an arbovirus of the Bunyaviridae family, genus Nairovirus: spherical or ellipsoidal in shape, 90-105 nm in size; covered with a lipid-containing membrane with spikes.

Crimean hemorrhagic fever

Crimean hemorrhagic fever (Crimean-Congo-Khazer hemorrhagic fever, Central Asian hemorrhagic fever, acute infectious capillary toxicosis, Crimean-Congo fever) is an acute viral natural focal infectious disease with a transmissible mechanism of pathogen transmission, characterized by fever, general intoxication, severe hemorrhagic syndrome and severe course. Crimean hemorrhagic fever is classified as a dangerous infectious disease.

Hemorrhagic fever with renal syndrome - Treatment

Treatment of hemorrhagic fever with renal syndrome is carried out in the initial period, in the first 3-5 days: ribavirin 0.2 g 4 times a day for 5-7 days