Diseases of the immune system (immunology)

Allergic diseases and other hypersensitivity reactions: causes, symptoms, diagnosis, treatment

Allergic diseases and other hypersensitivity reactions are the result of an inadequate, overly pronounced, immune response, not corresponding to the severity of the disease or infectious process.

Insufficiency of ZAP-70: causes, symptoms, diagnosis, treatment

The inadequacy of ZAP-70 (zeta-a-associated protein-70; ZAP-70-zeta-associated protein-70) leads to a disruption in T-lymphocyte activation, which causes defects in signaling systems.

X-linked lymphoproliferative syndrome (Duncan syndrome): causes, symptoms, diagnosis, treatment

The lymphoproliferative syndrome linked to the X chromosome is the result of a defect of T-lymphocytes and natural killers and is characterized by an abnormal response to infections caused by the Epstein-Barr virus, leading to liver damage, immunodeficiency, lymphoma, fatal lymphoproliferative disease, or bone marrow aplasia.

X-linked agammaglobulinemia (Bruton's disease)

X-linked agammaglobulinemia is a disease that is accompanied by the development of a low level of immunoglobulins or their absence, which often leads to the development of recurrent infections.

Wiskott-Aldrich syndrome: causes, symptoms, diagnosis, treatment

Wiskott-Aldrich syndrome is characterized by impaired co-operation between B- and T-lymphocytes and is characterized by recurrent infections, atopic dermatitis and thrombocytopenia.

Transient hypogammaglobulinemia of early age: causes, symptoms, diagnosis, treatment

Transient hypogammaglobulinemia of early age is a temporary decrease in serum IgG and sometimes IgA and other isotypes of Ig to a level below the age norms.

Severe combined immunodeficiency: causes, symptoms, diagnosis, treatment

Severe combined immunodeficiency is characterized by the absence of T-lymphocytes and low, high or normal amounts of B-lymphocytes and natural killers. Most infants develop opportunistic infections during 1 -3 months of life.

Lack of adhesion of leukocytes: causes, symptoms, diagnosis, treatment

Lack of adhesion of leukocytes is a consequence of a defect in adhesion molecules, which leads to dysfunction of granulocytes and lymphocytes and the development of recurrent infections of soft tissues.

Syndrome of hyperimmunoglobulinemia IgM

Hyperimmunoglobulinemia IgM syndrome is associated with immunoglobulin deficiency and is characterized by a normal or elevated serum IgM level and the absence or decreased amount of other serum immunoglobulins, leading to increased susceptibility to bacterial infections.

Hyperimmunoglobulinemia IgE Syndrome: Causes, Symptoms, Diagnosis, Treatment

Syndrome of hyperimmunoglobulinemia IgE combines T- and B-cell insufficiency and is characterized by recurrent staphylococcal abscesses of the skin, lungs, joints, internal organs that begin in early childhood.