Infectious and parasitic diseases

Hepatitis B: treatment

Patients with viral hepatitis B are necessarily hospitalized in an infectious diseases hospital. In mild cases, basic therapy is limited (diet No. 5, fractional drinking, gentle exercise). Patients with moderate cases, according to certain indications (severe intoxication, changes in biochemical parameters that are alarming in terms of the development of a severe course), undergo detoxification therapy: 5% glucose solution, polyionic solutions are administered intravenously, up to 500-1000 ml / day.

Hepatitis B: diagnosis

Diagnosis of hepatitis B is based on the analysis of cumulative clinical and laboratory data. The clinical symptoms include a gradual onset of the disease with normal or subfebrile body temperature, the prevalence of infectious asthenia in the form of general lethargy, weakness, muscle or joint pain, and the appearance of skin rashes.

Hepatitis B: symptoms

During acute hepatitis B, pre-icteric, icteric and convalescence periods are distinguished. The disease begins instantly. The pre-icteric period lasts 1-5 weeks. Asthenovegetative (weakness, fatigue, exhaustion) and dyspeptic (loss of appetite, decreased taste sensations, nausea, sometimes vomiting, bitterness in the mouth, heaviness and dull pain in the right hypochondrium) syndromes are characteristic.

Pathogenesis of hepatitis B

The hepatitis B virus enters the blood and then into hepatocytes, where its replication mainly occurs. Replication is also possible in the cells of the bone marrow, pancreas, kidneys, lymphocytes, but with less intensity. After the virus is adsorbed on the surface of the hepatocyte, its outer membrane is destroyed and the core particle (nucleocapsid) penetrates into the cell and then into its nucleus.

Hepatitis B

Viral hepatitis B, or hepatitis B, is a viral anthroponotic infectious disease with contact and vertical mechanisms of pathogen transmission. It is characterized by cyclically occurring parenchymatous hepatitis with the presence of jaundice in some cases and possible chronicity.

Hepatitis E

Viral hepatitis E is an acute viral disease with a fecal-oral mechanism of transmission of the pathogen, which is characterized by a cyclical course and frequent development of acute liver encephalopathy in pregnant women.

Hepatitis A treatment

Treatment of hepatitis A is currently usually carried out in an infectious diseases hospital, but given that hepatitis A in most cases occurs in a mild form and there are practically no malignant forms or chronic hepatitis, treatment can be carried out at home.

Hepatitis A - Diagnosis

Diagnosis of hepatitis A is based on clinical, epidemiological and laboratory data. The information content of these components is not the same. Clinical signs can be classified as supporting, epidemiological signs - as suggestive, while the results of laboratory studies are of decisive importance at all stages of the disease.

Hepatitis A - Symptoms

Symptoms of hepatitis A are characterized by a wide range of clinical signs: from inapparent subclinical forms, occurring without clinical symptoms, to clinically expressed forms with pronounced symptoms of intoxication and rather severe metabolic disorders.

Hepatitis A - Causes and Pathogenesis

The causative agent of viral hepatitis A is the HAV virus (hepatitis A virus), which belongs to the genus Hepatovirus in the family Picornaviridae. Morphologically, HAV looks like a small, non-enveloped spherical particle measuring 27-30 nm. The genome is represented by a single-stranded RNA molecule consisting of approximately 7500 nucleotides.