Diseases of the skin and subcutaneous tissue (dermatology)

Angiomatosis hereditary familial hemorrhagic: causes, symptoms, diagnosis, treatment

Hereditary familial hemorrhagic angiomatosis is an autosomal dominant disease. There are several reports in the literature that the disease has been found in several generations.

Juvenile polyfibromatosis of Rayne's fingers: causes, symptoms, diagnosis, treatment

The causes and pathogenesis of juvenile polyfibromatosis of the fingers of Rayne have not been fully established. It is believed that the dermatosis has an autosomal dominant type of inheritance.

Familial acrogeria (Gottron syndrome): causes, symptoms, diagnosis, treatment

Acrogeria familialis (Gottron syndrome) is a rare disease described in 1941 by H. Gottron. The causes and pathogenesis of Acrogeria familialis (Gottron syndrome) have not been fully studied. The development of the disease is largely due to disruption of the structure and function of fibroblasts and collagen synthesis, and hypofunction of the pituitary gland. There are reports of familial cases of the disease.

Tuberous sclerosis

Tuberous sclerosis is a hereditary disease characterized by hyperplasia of ecto- and mesoderm derivatives. The inheritance pattern is autosomal dominant. Mutant genes are located in loci 16p13 and 9q34 and encode tuberins, proteins that regulate the GT-phase activity of other extracellular proteins.

Erythrokeratoderma: causes, symptoms, diagnosis, treatment

Currently, this group of erythrokeratodermia includes skin keratinization disorders of the hyperkeratosis type and occurring on an erythematous background. However, few dermatologists classify it as an ichthyosis.

Pigment retention (Bloch-Sulzberg melanoblastosis)

Causes and pathogenesis of pigment incontinence (Bloch-Sulzberg melanoblastosis). Pigment incontinence is caused by a mutant dominant gene localized in the X chromosome.

Hartnup's disease: causes, symptoms, diagnosis, treatment

Hartup's disease is considered autosomal recessive. It was described in 1956 by DN Baron et al. The disease is characterized by a pellagroid rash, neuropsychiatric changes and aminoaciduria.

Favre-Rokusho disease (nodular elastosis of the skin with cysts and camedones): causes, symptoms, diagnosis, treatment

The causes and pathogenesis of the disease are unknown. According to many scientists, the dermatosis is hereditary. It occurs under the influence of prolonged solar insolation and other factors. The disease is more common among people working in the sun.

Papillary pigment dystrophy of the skin (black acanthosis)

Acanthosis nigricans (papillary-pigmented skin dystrophy) is characterized by hyperkeratosis, hyperpigmentation and papillomatosis of the skin, armpits and other large folds.

Lentiginosis periorificialis: causes, symptoms, diagnosis, treatment

The disease belongs to the group of hereditary lentigines, which, in addition to Peutz-Jeghers-Touraine syndrome, includes congenital and centrofacial lentigines.