Diseases of the liver and biliary tract

Autoimmune Hepatitis - Diagnosis

Some types of autoimmune hepatitis have no clearly identified cause, while others are associated with known agents such as thienic acid (a diuretic) or with diseases such as hepatitis C and D. In general, autoimmune hepatitis of unknown etiology has a more dramatic clinical picture, with higher serum transaminase activity and γ-globulin levels, liver histology suggesting higher activity than in cases of known etiology, and a better response to corticosteroid therapy.

Autoimmune hepatitis

Autoimmune hepatitis is a chronic hepatitis of unknown etiology, in the pathogenesis of which autoimmune mechanisms play a leading role. The disease is more common in women (the ratio of men and women in autoimmune hepatitis is 1:3), the most frequently affected age is 10-30 years.

Chronic hepatitis D

Chronic hepatitis D is the outcome of acute viral hepatitis D, occurring as a superinfection in chronic carriers of HBV markers. The frequency of chronicization of HDV infection is 60-70%.

Chronic Hepatitis - Classification

In 1968, De Groot et al. published a classification of chronic hepatitis in the Lancet journal, which was approved by the European Association for the Study of the Liver. The classification is based on the identification of morphological variants of chronic hepatitis. The authors proposed identifying the following morphological variants of chronic hepatitis.

Chronic Hepatitis - Causes

The most common cause of chronic hepatitis is acute viral hepatitis. Currently, the possibility of chronicization of four of the seven forms of acute viral hepatitis - B, C, D, G - has been established.

Chronic hepatitis

Chronic hepatitis is a polyetiological diffuse inflammatory process in the liver, lasting more than 6 months (Recommendations of the European (Rome, 1988) and World (Los Angeles, 1994) Congresses of Gastroenterologists). Unlike liver cirrhosis, chronic hepatitis does not disrupt the liver architecture.