Diseases of the gastrointestinal tract (gastroenterology)

Ischemic bowel disease

Ischemic bowel disease (abdominal ischemic disease) is an acute or chronic insufficiency of blood supply in the basins of the celiac, superior or inferior mesenteric arteries, leading to insufficient blood flow in individual areas or in all parts of the intestine.

Specific forms of chronic colitis

Eosinophilic enterocolitis (or gastroenteritis) is a manifestation of a type I allergic reaction to a food allergen, which is not always possible to identify. People aged 30-45 years are most often affected.

Allergic intestinal lesions

The damage to the small and large intestines can be an independent and the only manifestation or one of the components of the general allergic reaction of the body. Most often, entero- and colopathy occur with food and drug allergies, less often - with serum sickness, polyposis and other forms of general allergosis.

Crohn's Disease - Treatment

Treatment of Crohn's disease today is carried out according to empirical principles, that is, by selecting drugs that have antibacterial, anti-inflammatory and immunosuppressive effects.

Crohn's Disease - Diagnosis

In the initial stage of the disease, against the background of a dull (not shiny) mucous membrane, erosions-aphthae surrounded by whitish granulations are visible. Mucus and pus are visible in the lumen of the intestinal walls. As the disease progresses and the activity of the process increases, the mucous membrane unevenly thickens, acquires a whitish appearance, large ulcers (superficial or deep) appear, often longitudinally located, and a narrowing of the intestinal lumen is noted (a picture of a cobblestone pavement).

Crohn's Disease - Symptoms

General symptoms are caused by intoxication and malabsorption syndrome and include: weakness, malaise, decreased performance, increased body temperature to subfebrile, weight loss, edema (due to loss of protein), hypovitaminosis (bleeding gums, cracks in the corners of the mouth, pellagroma dermatitis, deterioration of twilight vision), pain in bones and joints.

Crohn's Disease - Causes and Pathogenesis

The etiology of Crohn's disease is unknown. The infectious nature of the disease is most widely discussed. It is assumed that Crohn's disease is associated with viruses, chlamydia, yersinia, and intestinal microbiocenosis disorders (a decrease in the number of bifidobacteria with a simultaneous increase in the number of pathogenic enterobacteria, anaerobic microorganisms, and potentially pathogenic strains of E. coli).