Transplantation

Kidney transplantation

Kidney transplantation is the most common type of solid organ transplantation; the main indication is end-stage renal failure.

Hematopoietic stem cell transplantation: procedure, prognosis

Hematopoietic stem cell transplantation (HSCT) is a rapidly developing technology that has the potential to provide a cure for malignant blood diseases (leukemia, lymphoma, myeloma) and other hematological diseases (e.g. primary immunodeficiency, aplastic anemia, myelodysplasia).

Heart transplantation

Heart transplantation is an opportunity for patients with end-stage heart failure, coronary artery disease, arrhythmias, hypertrophic cardiomyopathy or congenital heart disease, who have a high risk of death and symptoms so severe that they preclude the optimal use of drugs and medical equipment.

Post-transplant complications

Rejection of solid organs can be fulminant, accelerated, acute or chronic (late). These types of rejection overlap to some extent in time, but differ in the histological picture. Symptoms of rejection vary depending on the organ.

Immunosuppressive therapy in transplantation

Immunosuppressants suppress graft rejection and the primary response to transplantation itself. However, they suppress all types of immune response and play a role in the development of numerous post-transplant complications, including death from severe infections.

Transplantation: general information

Transplantation can be performed using the patient's own tissues (autotransplantation; for example, bone, skin graft), genetically identical (syngeneic) donor tissues (isotransplantation)