The most important plasma protein is albumin, solutions of which are widely used in surgical practice. Experience shows that the use of albumin solutions is the "gold standard" of transfusion therapy for critical conditions caused by hypovolemia and intoxication.
For quite a long time, preserved donor blood was considered the most effective and universal means of treating hemorrhagic anemia, hypovolemic conditions, protein metabolism disorders of various etiologies, etc.
Red blood cell mass (RBC) is a blood component consisting of red blood cells (70-80%) and plasma (20-30%) with an admixture of white blood cells and platelets (hematocrit - 65-80%). In terms of red blood cell content, one dose of red blood cell mass (270 ± 20 ml) is equivalent to one dose (510 ml) of blood.
Therapeutic hemapheresis includes plasmapheresis and cytapheresis, which are generally tolerated by healthy donors. However, there are many minor and some significant risks.
Before starting a transfusion, it is necessary to check the container labeling and perform compatibility tests to ensure that the component is intended for the recipient.
Whole blood transfusion improves the oxygen capacity of the blood, restores volume, clotting factors and was previously recommended for massive blood loss.
More than 23 million units of blood components are transfused annually in the United States. Although transfusion procedures are now much safer than they once were, the risks (and public perception of risk) require informed patient consent for transfusion in all cases.
