In case of congenital cytomegalovirus infection, the nature of the fetal damage depends on the period of infection. Acute cytomegalovirus infection in the mother in the first 20 weeks of pregnancy can lead to severe fetal pathology, which results in spontaneous miscarriage, intrauterine death of the fetus, stillbirth, defects, in most cases incompatible with life. In case of infection with cytomegalovirus in the late stages of pregnancy, the prognosis for the life and normal development of the child is more favorable.