Diseases of the endocrine system and metabolic disorders (endocrinology)

Isolated hypogonadotropic ovarian hypofunction

Occurs as a result of insufficient stimulation of ovarian function by gonadotropic hormones (GH) of the pituitary gland. Reduced or inadequate secretion of GH by the pituitary gland may be observed with damage to its gonadotrophs or with decreased stimulation of gonadotrophs by luteinizing hormone of the hypothalamus, i.e. secondary ovarian hypofunction may be of pituitary genesis, hypothalamic and, more often, mixed - hypothalamic-pituitary.

Depleted ovary syndrome

Primary ovarian hypofunction of the ovaries includes the so-called syndrome of exhausted ovaries. Many terms have been proposed to characterize this pathological condition: "premature menopause", "premature menopause", "premature ovarian failure", etc.

Ovarian hypofunction

Ovarian hypofunction, which occurs as a result of damage at the level of the ovary itself, is primary. This form also varies in pathogenesis.

Endocrine diseases

In recent years, modern endocrinology has made significant progress in understanding the diverse manifestations of the influence of hormones on the body's vital processes.

Ectopic ACTH production syndrome - Overview of information

In 1928, WH Brown first described a patient with oat cell lung cancer who had clinical manifestations of hypercorticism: characteristic obesity, striae, hirsutism, and glucosuria.

Symptoms of pheochromocytoma (chromaffinoma)

Patients with chromaffinoma can be divided into two groups. The first are cases of so-called silent tumors. Such formations are found during autopsy of patients who died from various causes, without a history of hypertension.

Causes and pathogenesis of pheochromocytoma (chromaffinoma)

About 10% of all cases of neoplasms from chromaffin tissue are related to the familial form of the disease. Inheritance occurs according to the autosomal dominant type with high variability in the phenotype. As a result of the study of the chromosomal apparatus in the familial form, no deviations were revealed.

Pheochromocytoma (chromaffinoma) - Information Overview

Pheochromocytoma is a catecholamine-secreting tumor of the chromaffin cells typically located in the adrenal glands. It causes persistent or paroxysmal hypertension. Diagnosis is based on measuring catecholamine products in the blood or urine. Imaging, especially CT or MRI, helps localize tumors. Treatment involves removing the tumor if possible.

Treatment of congenital adrenal cortex dysfunction

Treatment of congenital adrenogenital syndrome consists of eliminating the deficiency of glucocorticoids and hyperproduction of corticosteroids, which have an anabolic and virilizing effect.

Causes and pathogenesis of congenital adrenal cortex dysfunction

Congenital adrenogenital syndrome is genetically determined and is expressed in the deficiency of enzyme systems that ensure the synthesis of glucocorticoids; it causes increased secretion of ACTH by the adenohypophysis, which stimulates the adrenal cortex, which secretes mainly androgens in this disease.