Treatment of tumors of the renal pelvis and ureter involves surgical intervention, as well as the use of conservative methods, such as chemotherapy and radiation therapy.
The most common symptom of a tumor of the renal pelvis and ureter, which occurs with a frequency of 75%, is hematuria. Also, a manifestation of this disease is pain in the lumbar region.
Tumors of the renal pelvis and ureter have still unknown causes. Smoking is a risk factor that increases the risk of developing transitional cell carcinoma of the upper urinary tract by 3 times. About 70% of men and 40% of women who get sick are smokers.
The average age of patients with tumors of the renal pelvis and ureter is 65 years. The incidence increases with age, but tumors of the upper urinary tract are a rare autopsy finding.
In 60% of cases, the cause of Wilms' tumor is the result of a somatic mutation, in the remaining 40% of cases it is the result of hereditary-determined mutations.
Wilms' tumor, or so-called nephroblastoma, accounts for about 6% of all malignant tumors in childhood. It is named after the surgeon Max Wilms, who discovered it.