Diseases of the gastrointestinal tract (gastroenterology)

Neurotensinoma: causes, symptoms, diagnosis, treatment

Neurotensinoma - individual neurotensin-producing cells (N-cells) are found in pancreatic gastrinoma. There are still few reports of predominantly neurotensin-producing tumors.

Multiple endocrine adenomatosis: causes, symptoms, diagnosis, treatment

A hormonally active tumor of the pancreas can be one of the manifestations of multiple endocrine adenomatosis (MEA) or multiple endocrine neoplasia (MEN).

Pancreatic carcinoid.

Carcinoid tumor of the pancreas is found mainly in middle-aged and elderly people. It can be localized in any part of the pancreas. The tumor size varies from a few millimeters to 13-14 cm.

Glucagonoma is an A-cell pancreatic tumor that produces glucagon, clinically manifesting itself as a combination of characteristic skin changes and metabolic disorders. The glucagonoma syndrome was deciphered in 1974 by C. N. Mallinson et al. In 95% of cases, the tumor is located intrapancreatically, in 5% - extrapancreatically. Only cases of solitary tumors were observed. In more than 60% of patients, it is malignant. Sometimes glucagonoma produces other peptides - insulin, PP.

Werner-Morrison syndrome

Werner-Morrison syndrome is a disease that manifests itself as severe, treatment-resistant watery diarrhea, hypokalemia, and gastric achlorhydria or hypochlorhydria and is also called WDHA or WDHH syndrome (Hypokalemia Achlorhydria, Hypochlorhydria).

Insulinoma

Insulinoma is the most common endocrine tumor of the pancreas. It accounts for 70-75% of hormonally active tumors of this organ. Insulinoma can be solitary and multiple, in 1-5% of cases the tumor is a component of multiple endocrine adenomatosis.

Hormone-active pancreatic tumors: causes, symptoms, diagnosis, treatment

Most hormonally active tumors of the digestive system are localized in the pancreas. This is due to the abundance of hormonally competent cells in it, from which such tumors originate.

Pancreatic sarcoma

Pancreatic sarcoma is extremely rare; to date, about 200 cases of pancreatic sarcoma have been described in specialized medical literature (according to the combined statistics of a number of authors).

Pancreatic Cancer - Symptoms

The symptoms of pancreatic cancer are polymorphic and largely depend on the location, type and size of the tumor, its relationship to nearby organs, the duration of the disease (stage), the presence or absence of metastases. The symptoms of the initial stage of pancreatic carcinoma are rather vague: weight loss, anorexia, dyspepsia, weakness, loss of ability to work; their frequency varies.

Pancreatic cancer

Pancreatic cancer occurs, according to various sources, in 1-7% of all cancer cases; more often in people over 50 years of age, mainly in men.