Serological tests

Toxocarosis: serum antibodies to Toxocara canis

The main method for diagnosing toxocariasis is the detection of IgG antibodies to Toxocara canis in the blood serum using the ELISA method with the toxocara antigen when examining the blood serum of individuals with a characteristic complex of symptoms: lymphadenopathy, hepatomegaly, bronchitis, bronchial asthma of unknown genesis, urticarial rash against the background of blood eosinophilia, leukemoid reaction of the eosinophilic type with a characteristic epidemic history (for example: geophagy), etc.

Echinococcosis: antibodies to echinococcus in the blood

The most effective method for diagnosing echinococcosis is the ELISA method. However, the use of this method is limited by the fact that many carriers of echinococcosis cysts do not develop an immune response, and antibodies are not formed in the blood. ELISA gives positive results in 90% of patients with cysts in the liver and only in 50-60% of patients with lung damage.

Lambliasis: determination of antibodies to Giardia antigens in blood

Existing ELISA test systems allow for the detection of specific antibodies of different classes (IgM, IgA, IgG) or total antibodies separately. IgM antibodies to lamblia antigens are detected in the blood on the 10th-14th day after invasion.

Toxoplasmosis: determination of IgM and IgG antibodies to toxoplasm in blood

Early diagnosis of toxoplasmosis is especially important for pregnant women due to the risk of intrauterine infection of the fetus, which can lead to fetal death (spontaneous abortion) or the birth of a child with serious lesions.

Amoebiasis: antibodies to Entamoeba histolytica in blood

The diagnosis of intestinal amebiasis is established based on the detection of the pathogen in feces or tissues (biopsy is examined) using special dyes. In feces, Entamoeba hystolitica antigens (adhesin) can be detected using the ELISA method.

Antibodies to Mycoplasma hominis in blood

Using ELISA, it is possible to determine IgM and IgG antibodies to Mycoplasma hominis. This method is more sensitive and specific (92% and 95%, respectively) than others.

Detection of Ureaplasma urealiticum antigen by direct immunofluorescence method

Ureaplasma urealiticum is classified as a mycoplasma. The name "ureaplasma" comes from the ability of this mycoplasma species to synthesize the enzyme urease, which breaks down urea to form carbon dioxide and ammonia.

Detection of Mycoplasma hominis antigen by direct immunofluorescence method

In men, mycoplasmas (Mycoplasma hominis, Ureaplasma urealyticum) most often cause urethritis, in women - endometritis and salpingitis, in newborns they can cause meningitis, respiratory infections, septicemia.

Antibodies to Mycoplasma pneumoniae in blood

Serological diagnostics is based on the detection of the titer of antibodies to Mycoplasma pneumoniae in serum. The most widely used method is the ELISA.

Respiratory mycoplasmosis: detection of Mycoplasma pneumoniae antigen by direct immunofluorescence

Mycoplasma pneumoniae is a pathogen of the human respiratory tract that parasitizes on cell membranes. The proportion of respiratory mycoplasmoses in the general group of respiratory diseases varies for different population groups from 35% to 40%. Mycoplasma pneumonias account for 10-17% of the total number of pneumonia cases.