Stem cells

Hematopoietic bone marrow stem cells and bone marrow transplantation

Cell transplantation began not with embryonic stem cell derivatives, but with bone marrow cell transplants. The first studies on experimental bone marrow transplantation almost 50 years ago began with an analysis of the survival of animals exposed to total irradiation followed by an infusion of bone marrow hematopoietic cells.

Hematopoietic stem cells of the yolk sac

Obviously, the various proliferative and differentiating potentials of hematopoietic stem cells are determined by the peculiarities of their ontogenetic development, since during the process of ontogenesis in humans even the localization of the main areas of hematopoiesis changes.

Hematopoietic stem cells from umbilical cord blood

Umbilical cord blood is a good source of hematopoietic stem cells in terms of proliferative potential and repopulation capabilities of hematopoietic cells.

Hematopoietic stem cells

Hematopoietic stem cells (HSCs), like mesenchymal progenitor cells, are characterized by multipotency and give rise to cell lines, the final elements of which form the formed elements of the blood, as well as a number of specialized tissue cells of the immune system.

Mesenchymal stem cells

Among regional stem cells, a special place is occupied by mesenchymal stem cells (MSCs), the derivatives of which make up the stromal matrix of all organs and tissues of the human body.

Neural stem cells

It has been established that neural stem cells express glial acidic fibrillary protein, which among mature cells of the neural lineage is retained only on astrocytes.

Limitations, dangers and complications of cell transplantation

Regenerative plastic medicine is based on the clinical implementation of the toti- and pluripotent properties of embryonic and progenitor stem cells, which allow in vitro and in vivo the creation of specified cell lines that repopulate damaged tissues and organs of a sick person.

Embryonic stem cells

The discovery of embryonic stem cells did not arise by chance, but emerged on the prepared ground of scientific research in the field of developmental biology. The term “stem cell” was introduced into medicine in 1908 at the congress of the hematological society in Berlin by Alexander Maximov in relation to hematopoietic cells.

Stem cells and regenerative and plastic medicine

Today, few practicing doctors do not know about the development of a new direction in the treatment of severe diseases, previously incurable by traditional and alternative medicine. We are talking about regenerative-plastic medicine, based on the use of the regenerative potential of stem cells.