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Investigation of enzymes and isoenzymes

Liver tests in pregnancy

Both at the stage of pregnancy planning and during pregnancy, a woman regularly undergoes a series of laboratory tests to assess the general condition of the body and promptly identify any pathological changes.

Blood tests for liver tests: what is included?

A screening study aimed at assessing the functional state of the biliary system and liver is an analysis of liver function tests. Diagnostics are performed by taking blood.

Blood tests for liver tests in a child

The tests are selected based on the baby’s age, growth and hormonal characteristics, the presence of congenital anomalies and chronic diseases of the body.

Blood test for liver tests: preparation, how to take, what shows

The liver is the largest gland in the human body. It occupies the upper right section of the abdominal cavity, located under the diaphragm.

Lactate dehydrogenase isoenzyme 1 in blood

Lactate dehydrogenase isoenzymes are contained in tissues in a strictly defined ratio, that is, each tissue, including blood, has a characteristic spectrum of lactate dehydrogenase isoenzymes that is unique to it.

Troponin I in the blood

Troponin I is a structural protein of the muscle troponin complex with a molecular weight of 26,500 Da. Troponins I, like troponins T, of cardiac and skeletal muscles differ significantly in their amino acid sequence.

Troponin T in the blood

The troponin complex is part of the muscle contractile system. It is formed by three proteins: troponin T, which forms a bond with tropomyosin (molecular weight 3700), troponin I (molecular weight 26,500), which can inhibit ATPase activity, and troponin C (molecular weight 18,000), which has a significant affinity for Ca2+.

Myoglobin in the blood

Myoglobin is a heme-containing chromoprotein; it is a light chain of myosin with a molecular weight of 17.6 kDa. It is a protein that transports oxygen in skeletal muscles and the myocardium.

MB-fraction of creatine kinase in serum

Creatine kinase in the cardiac muscle consists of two isoenzymes: CK-MM (60% of total activity) and CK-MB (40% of total activity). CK-MB is a dimer, consisting of two subunits: M (muscle) and B (brain).

Total creatine kinase in the blood

Creatine kinase reversibly catalyzes the phosphorylation of creatine. Skeletal muscles and cardiac muscle are the richest in creatine kinase, and there is less of it in the brain, thyroid gland, uterus, and lungs.