All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Thyroglobulin in the blood
Medical expert of the article
Last reviewed: 05.07.2025
Reference values (norm) for thyroglobulin concentration in blood serum are 3-42 ng/ml (mcg/l).
Thyroglobulin is a precursor of thyroid hormones T3 and T4, used as a marker of neoplasms in the thyroid gland, and in patients with a removed thyroid gland or treated with radioactive iodine, to assess the effectiveness of the treatment. Relapses of benign and malignant tumors of the thyroid gland are accompanied by an increase in the concentration of thyroglobulin in the blood in most patients. The concentration of thyroglobulin is increased in patients with subacute thyroiditis, as well as in patients with relapses of chronic nonspecific thyroiditis.
Diseases and conditions in which the concentration of thyroglobulin in the blood serum changes
Thyroglobulin is elevated |
Thyroglobulin is reduced |
Thyroid tumors Subacute thyroiditis Thyroid cancer metastases Iodine deficiency Graves' disease Condition after treatment with radioactive iodine |
Thyroid hormone overdose |