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Pain relieving suppositories for periods
Medical expert of the article
Last reviewed: 03.07.2025

Indications pain relieving suppositories during menstruation.
Typically, such drugs are recommended for symptomatic treatment of inflammatory diseases of the genitourinary system. Due to their combined composition, they cope well not only with unpleasant pain, but also with inflammation, so they are often prescribed by gynecologists to reduce pain during menstruation.
Release form
In vaginal suppositories with an analgesic effect, the main component is always an analgesic. For example, the following have become popular recently:
Efferalgan. An analgesic whose active ingredient is paracetamol. It has anti-inflammatory and antipyretic effects. It is intended for the treatment of mild to moderate pain syndromes (headaches, myalgia, toothache, menstrual pain, neuralgia).
The dosage for adult patients is 500 mg, and suppositories can be used no more than four times a day. Therapy continues for five to seven days. If the pain does not stop, you should consult a doctor.
Do not use the drug if you are intolerant to paracetamol. The effect of this substance on fetal development has not been studied, but during pregnancy and breastfeeding, you should use this drug with caution.
Main side effects: hepatotoxic effect (with long-term use), leukopenia, neutropenia, allergy.
Paracetamol. Cream or white suppositories, the active ingredient of which is paracetamol. They have an antipyretic, anti-inflammatory, analgesic effect.
The drug is taken up to five times a day (one suppository). It is very important to use suppositories at the same interval (four hours). It is not recommended to take it for more than five days to achieve a pain-relieving effect. If you do not get the desired result, you should consult a doctor.
The drug should be taken with special caution in case of kidney and liver diseases, as well as in case of intolerance to paracetamol. With frequent use of suppositories, side effects may occur: allergies (urticaria, itching, skin rashes), thrombocytopenia or anemia.
Cefekon D. The active ingredient of these suppositories is paracetamol, which has excellent antipyretic and analgesic effects. Can be used to reduce temperature, relieve pain during headaches, neuralgia, toothache, menstruation.
The dosage of the drug is prescribed individually. It depends on the severity of the symptoms. Usually, the drug is used up to three times a day, 500 mg each. The intervals between doses should be up to six hours.
The drug is not recommended for use in cases of paracetamol intolerance and liver disease. The main side effects include: nausea, vomiting, allergies, thrombocytopenia, anemia.
Rectal pain relief suppositories for menstruation
In case of severe pain during menstruation, it is the suppositories that allow you to get a quick and fairly stable pain-relieving effect. Usually, such suppositories are inserted rectally and begin to act within 15-30 minutes after use.
Tylenol. Although these suppositories are usually prescribed to reduce fever (at elevated temperatures), they can also be used during menstruation. The active ingredient in the suppositories is paracetamol.
Rectal suppositories are recommended to be used no more than four times a day at a dosage of 500 mg. If there is no relief after three to five days, you should stop taking them and consult a doctor.
The drug is contraindicated if you are allergic to paracetamol, as well as newborn children. Use suppositories with caution in case of kidney and liver diseases, viral hepatitis, alcoholism, diabetes. Also, do not take the drug during pregnancy.
When using Tylenol suppositories, the effectiveness of the drugs that are designed to remove uric acid is reduced. The most well-known side effects are: anemia, erythema, headache, nausea, vomiting, cyanosis, allergy.
Acamol-Teva. The active ingredient of the drug is paracetamol, as in most similar analgesic rectal suppositories. It is used to treat mild to moderate pain (headache, toothache, miralgia, fever, menstrual pain).
The dosage is no more than 500 mg. The drug should not be used more than four times a day. The duration of therapy is five to seven days. If relief does not occur during this period, the treatment is stopped.
Suppositories should not be used in case of paracetamol intolerance, in early childhood, kidney disease, alcoholism, diabetes, during breastfeeding. The main side effects of taking the drug are: dizziness, nausea, vomiting, allergy, swelling, irritation of the rectum.
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Pharmacodynamics
Let's consider the pharmacodynamics and pharmacokinetics of pain-relieving suppositories during menstruation using the well-known drug "Paracetamol" as an example.
This drug is a non-narcotic analgesic, the action of which is based on blocking COX 2 and COX 1 in the central nervous system, due to the effect on the thermoregulation and pain centers. The drug does not negatively affect the mucous membranes of the rectum or gastrointestinal tract (depending on the form of release) and water-salt metabolism in the body.
Pharmacokinetics
It is characterized by a fairly high absorption. When breastfeeding, it is worth noting that at least 1% of the substance enters breast milk. The drug is metabolized in the liver. Paracetamol is excreted through the kidneys in the form of metabolites. At the same time, only 3% of the substance is excreted unchanged.
Dosing and administration
The effect of suppositories during menstruation is more effective. They are especially often used if a woman also experiences nausea and vomiting. They are usually used twice a day, one suppository at a time. The time intervals between doses should be long enough. In case of severe pain, suppositories are used up to 4 times.
Contraindications
Suppositories with an analgesic effect are prohibited to use only in a few cases: with alcohol abuse, intolerance to paracetamol and during breastfeeding. It is also worth carefully calculating the dosage for liver and kidney diseases, diabetes, blood diseases.
Side effects pain relieving suppositories during menstruation.
Side effects from taking rectal suppositories with an analgesic effect are quite rare. Some patients develop an allergic reaction (swelling, redness, rash, hives, itching). In such cases, it is recommended to immediately stop treatment.
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Interactions with other drugs
Storage conditions
Suppositories should be stored in a dry place protected from direct sunlight. The temperature should not exceed 15 degrees. After opening the package, it is better to store in the refrigerator for ease of use of suppositories.
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Attention!
To simplify the perception of information, this instruction for use of the drug "Pain relieving suppositories for periods" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.