^
Fact-checked
х

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.

We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.

If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.

Total number of T-lymphocytes (CD3) in the blood

Medical expert of the article

Pediatric immunologist
, medical expert
Last reviewed: 05.07.2025

Normally, the relative total number of T-lymphocytes in the blood of adults is 58-76%, the absolute number is 1.1-1.7×10 9 /l.

Mature T-lymphocytes are responsible for cellular immunity reactions and perform immunological surveillance of antigen homeostasis in the body. They are formed in the bone marrow and differentiate in the thymus gland, where they are divided into effector (killer T-lymphocytes, delayed-type hypersensitivity T-lymphocytes) and regulatory (helper T-lymphocytes, suppressor T-lymphocytes) cells. Accordingly, T-lymphocytes perform two important functions in the body: effector and regulatory. The effector function of T-lymphocytes is specific cytotoxicity in relation to foreign cells. The regulatory function (T-helper-T-suppressor system) consists in controlling the intensity of the development of a specific reaction of the immune system to foreign antigens. The regulatory effects of T-lymphocytes on cells of the monocyte-macrophage series are varied. The ability of T-lymphocytes to synthesize and produce cytokines will allow them to participate not only in the regulation of immune functions, but also in many vital processes. Many diseases are based on T-lymphocyte pathology, which in some cases is directly related to their damage, and in others is mediated through a violation of immune regulation.


The iLive portal does not provide medical advice, diagnosis or treatment.
The information published on the portal is for reference only and should not be used without consulting a specialist.
Carefully read the rules and policies of the site. You can also contact us!

Copyright © 2011 - 2025 iLive. All rights reserved.