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Rossolimo-Melkerson-Rosenthal syndrome.
Medical expert of the article
Last reviewed: 07.07.2025
Rossolimo-Melkerson-Rosenthal syndrome is a chronically recurring dermatosis of unknown etiology.
In its development, importance is given to genetic factors, functional disorders of the nervous system such as angioneurosis, and infectious-allergic mechanisms. It manifests itself as a combination of granulomatous cheilitis (less often infiltration and swelling of other parts of the face), paresis (or paralysis) of the facial nerve and folded tongue.
Pathomorphology of Rossolimo-Melkerson-Rosenthal syndrome. In some cases the picture is non-specific, tissue edema is detected, in others granulomatous changes are observed, identical to those in sarcoidosis or Miescher's granulomatous cheilitis, sometimes perivascular and perifollicular granulomas are visible against the background of non-specific lymphocytic infiltration.
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