Itching between the fingers is one of the symptoms of many painful conditions. For example, this is often observed with dermatological problems, neurological pathologies, systemic and psychiatric diseases. Because of the constant itching, a person becomes emotionally unstable, irritable and even aggressive, or falls into depression.
The stimulating factor of the itch may be different. It is he who determines the basic tactics of treatment. As a rule, the problem originates when histamine-sensitive peripheral nerve endings are activated. Histamine-insensitive terminations are also involved in the transport of the itching sensation signal. At the same time, the responsibility for this signal, which is transferred to the center from the periphery, lies on histamine, opioids, protease, cathepsin, neural growth factor, interleukins, prostaglandins, gastrin-bound peptide. With a pain signal, a reflex of "alienation and avoidance" is observed, and when itching appears between the fingers, a reflex treatment is formed. So, combing, rubbing, pinching between the fingers gives one-time and short-time satisfaction. With severe discomfort, a person can comb the troublesome places before the wounds, which leads to the replacement of the sensation of itching with pain.
With constant itching, the cortex forms a zone of painful arousal. In turn, this leads to an excessive reaction of the skin to any stimuli. As a consequence, the threshold of susceptibility decreases, which significantly complicates the treatment of the disease.
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