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Comprehensive study of the immune status of the organism

Medical expert of the article

Pediatric immunologist
, medical expert
Last reviewed: 04.07.2025

Currently, clinical immunology has become a link between a number of medical disciplines. Its main tasks include diagnostics, prognosis and development of methods for treating human diseases accompanied by various defects of the immune system. Changes in the immune system during diseases should not be considered in isolation, but in combination with other important life support systems of the body. A comprehensive assessment of the state of various links of the immune system should take into account both quantitative and qualitative changes in immunity indicators. Methods of clinical immunology allow solving the following problems.

  • To identify defects in one or another part of the immune system (congenital and acquired immunodeficiencies).
  • To diagnose autoaggression against normal components of the body (autoimmune diseases) and excessive accumulation of immune complexes (immune complex diseases).
  • To identify dysfunctions in which signs of hyperfunction develop in one or another link of the immune system to the detriment of the functioning of other links (hypergammaglobulinemia, heavy chain disease, myeloma, etc.).
  • Monitor the effectiveness of immunosuppressive or immunostimulating therapy.
  • Conduct typing and selection of donors for organ transplants and monitor the administration of immunosuppressive therapy during transplants.
  • Conduct phenotyping of hemoblastoses.
  • To diagnose genetic predisposition to somatic diseases.

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