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Causes of IgA-carrying B-lymphocytes rise and fall

Medical expert of the article

Rheumatologist, immunologist
, Medical Reviewer, Editor
Last reviewed: 04.07.2025

Diseases and conditions that lead to changes in the number of B-lymphocytes carrying IgA

Increase in the indicator

Decrease in the indicator

Acute and chronic bacterial, fungal and parasitic infections

Chronic liver disease, cirrhosis

Rheumatoid arthritis

Systemic lupus erythematosus

Chronic lymphocytic leukemia

Endothelioma, osteosarcoma Myeloma Waldenstrom's macroglobulinemia Candidiasis, cystic fibrosis

Respiratory diseases (bronchial asthma, tuberculosis)

Monoclonal gammopathy

Physiological hypogammaglobulinemia (in children aged 3-5 months)

Congenital hypogammaglobulinemia or agammaglobulinemia

Diseases that lead to depletion of the immune system:

  • neoplasms of the immune system;
  • condition after spleen removal;
  • treatment with cytostatics and immunosuppressants

Acute viral infection

Chronic bacterial infection


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