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Biseptol for sore throat: how to take, dosages
Medical expert of the article
Last reviewed: 03.07.2025

Angina is a fairly common disease of the upper respiratory tract, which is accompanied by intense pain, cough, runny nose, reddened throat, inflammation of the tonsils and lymph nodes, and a sharp increase in temperature. Often, angina is accompanied by signs of intoxication. The main cause is a bacterial infection. In this case, mixed infection most often prevails, represented by an association of bacterial and viral infection with a significant prevalence of representatives of the streptococcal group. There are many methods for treating angina. One of the most effective drugs is Biseptol for angina.
Can Biseptol be used for tonsillitis?
Often in the therapist's office you have to hear the question: "Can Biseptol be used for tonsillitis?". So, the active antibacterial substance has an effect on both gram-positive and gram-negative microflora, and also relieves the inflammatory process, prevents stagnation, accelerates metabolic processes. Recovery occurs much faster.
ATC classification
Active ingredients
Pharmacological group
Indications Biseptol
It has bactericidal activity against cocci. A characteristic feature is that Biseptol helps to overcome the inflammatory and infectious process caused by chlamydial infection, mycobacteria, enterococci. It also helps with fungal and yeast-like flora. Indications for use are severe cough, burning, soreness, enlargement and pain in the lymph nodes, night snoring.
- Biseptol for purulent tonsillitis
It is one of the most effective remedies for purulent tonsillitis. Biseptol has been used in therapeutic and pediatric practice for a long time.
It is effective only when the cause of the development of angina is bacterial microflora.
Release form
There is only one known form of release of Biseptol - round tablets, having a yellow tint, but mostly white. They have engraving and a risk on one side. The composition includes sulfamethoxazole and trimethopril in a concentration of 400 and 80 mg, which is 480 mg in total. Additionally, there are auxiliary substances that do not have a therapeutic effect. Packed in cardboard boxes of 14 and 20 pieces.
Pharmacodynamics
Speaking about the pharmacodynamics of sulfamethoxazole, it is worth noting: it contributes to the disruption of synthetic processes in bacteria, respectively, metabolic processes are disrupted. Gradually, bacterial cells die, and the inflammatory process subsides.
As for the pharmacodynamics of trimethoprim, it acts as an enhancer of the activity of sulfamethoxazole, relieves inflammation, restores. Also, the action of this substance is aimed at restoring protein metabolism of the macro-organism and disrupting the synthesis processes in the microorganism.
In general, it is considered as a complex anti-inflammatory agent. A characteristic feature is that it can have dual effects: it prevents the development of intestinal infection. Side effects in the form of dysbacteriosis may develop.
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Pharmacokinetics
When talking about pharmacokinetics, the first thing to focus on is the drug's activity. It enters the bloodstream by absorption from the gastrointestinal tract after 2-3 hours of administration. The peak concentration in the blood is detected after about 3-4 hours. Then the substance begins to distribute itself throughout the tissues and biological fluids, exerting a therapeutic effect. First of all, it penetrates the respiratory tract and lymphoid organs, which is important in the treatment of angina.
The half-life is on average 8-17 hours and is determined by the activity of the kidneys and liver. The main part is excreted in the urine.
Dosing and administration
Prescribed for internal use. The tablet should be swallowed (washed down with clean water). The dosage is determined by age, based on the fact that the standard dose is 480 milligrams. Up to 5 years, half the standard dose is prescribed per day, from 5 to 12 years - 480 mg. After 12, 960 mg per day is allowed. For safety reasons, the method of application, optimal doses should be selected exclusively by a doctor.
- How to take Biseptol 480 for colds?
One of the most common questions that we hear from patients is the question "How to take Biseptol 480 for a cold." This is quite difficult, since many factors need to be taken into account.
Firstly, Biseptol may be effective if the cold is caused by bacterial microflora. When the cold is caused by viral microflora, there will be no result.
Secondly, it is necessary to choose the right dose. This is not difficult to do, since one tablet is a daily dosage.
Biseptol for sore throat in adults
Biseptol is recommended for purulent and lacunar tonsillitis in adults. It allows you to quickly eliminate the inflammatory and infectious process. Purulent tonsillitis is a direct indication for prescribing Biseptol, since the purulent process is almost always caused by bacterial microflora. Most often, Biseptol has an antibacterial effect, which allows you to quickly get rid of the infectious and purulent process.
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Application for children
Biseptol can be used for children, but not earlier than they are 3 years old. An approximate treatment regimen is selected based on laboratory tests and anamnesis data. It is recommended to take it for severe tonsillitis and its complicated forms. Half a tablet per day is enough.
- Biseptol for cough in children
It makes sense to prescribe Biseptol for a child's cough, provided that the cough is caused by a bacterial process and is a consequence of the development of tonsillitis. If the cough is caused by a viral process or an allergic reaction, the drug will not only not have the expected effect, but may even worsen the condition. Therefore, correct diagnosis and determination of the etiological factor are important.
It is worth noting that you should never make a decision on prescribing this drug to your child on your own, as this may be fraught with serious consequences and complications. You must consult a doctor who, based on the anamnesis data, as well as the results of examination and laboratory tests, will prescribe the appropriate treatment and select the dosage of the drug.
Use Biseptol during pregnancy
In general, the use of any medications, especially antibiotics, is contraindicated during pregnancy. But if the infection begins to progress, taking Biseptol is allowed, only as prescribed by a doctor. The main indication for this is lacunar tonsillitis.
This disease implies that the inflammatory process and infection spread to the lacunae of the throat, which have the appearance and shape of sacs filled with purulent contents. The inflammatory process develops in these lacunae, where bacterial microflora reproduces and develops. The lacunar form is especially difficult to treat, since almost the entire pathological process occurs in the lacunae and is not accessible to many drugs. Also, microorganisms reproduce there much more effectively, forming their own microenvironment (biofilm). But biseptol has the ability to penetrate the lacunae, destroy the microbial biofilm, and relieve the inflammatory process.
It is important to understand that this risk from the absence of treatment must be much higher than all possible risks of therapy. The dosage is strictly individual.
Contraindications
There are not many contraindications, but they are all quite serious, and must be taken into account. It is not recommended for use in cases of renal failure, diseases that are in remission (it creates an additional load, and the kidneys suffer from it first of all). There is also a load on the urinary system, the drug can cause intoxication, edema syndrome. For the same reason, it is advisable to prescribe it to pregnant women, children under 3 years old, with increased individual sensitivity, diseases of the stomach, intestines, especially gastritis, ulcers, pre-ulcer condition.
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Side effects Biseptol
It is considered a proven and relatively safe drug, so side effects are rare. Kidney and liver disorders are possible. There are disorders of urination or bile excretion, digestive disorders. As a result, an imbalance of metabolic processes, dysbacteriosis develops, which is accompanied by nephritis, pyelonephritis, cystitis, glomerulonephritis, and even renal failure. Edema, dermatitis, eczema, urticaria develop.
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Overdose
Overdose is accompanied by digestive pathologies: nausea, vomiting, diarrhea, flatulence. Signs of poisoning are observed. When the first symptoms of overdose appear, you need to provide emergency assistance as quickly as possible: induce vomiting, wash out the stomach. This will eliminate the substance from the body. You also need to immediately call an ambulance. In a polyclinic, detoxification, restorative, and supportive therapy are usually carried out.
Interactions with other drugs
It is relatively well tolerated by the body, and no specific interactions with other medications are noted. When analyzing reviews of the drug, I managed to find several mentions that an overdose may develop when taken with other antibiotics. The instructions indicate that the drug can react with antiviral agents.
It is not recommended to combine with secretion blockers, since the combined use of these agents inhibits excretory processes and disrupts kidney function, causes dysuric disorders, urinary syndrome, inflammatory process in the kidneys, diseases of the genitourinary system. Against the background of combined use with vitamins, vitamin-mineral complexes and biological additives, a reaction is observed that leads to a decrease in antibacterial activity.
Storage conditions
Biseptol should be stored in the original packaging. Usually, the storage conditions are specified in the instructions. You can store the drug at room temperature, in the refrigerator, on the door, on the bottom shelf. This is where the optimal temperature is located, which will allow you to maintain the active components that are part of the drug. It is important to store the tablets in a dry place. The temperature should not exceed 25 degrees. At the same time, direct sunlight should not fall.
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Shelf life
Biseptol can be stored for two years from the date of manufacture. Do not take the drug if the expiration date has expired, since there will be no effect from the treatment.
Analogues
The closest analogues of the drug are co-trimoxazole, sulfanilamide. These are pure substances that are part of biseptol. The drug can also be replaced with other antibiotics, such as rifampin, amoxiclav, amoxicillin, ampicillin.
- Co-trimoxazole
Co-trimoxazole is taken at 80 mg per day. It should be taken for at least 10 days. It should be taken into account that the drug has anticoagulant activity, thins the blood. Also, it cannot be taken in combination with anticoagulants, since their activity is sharply reduced. Also, there is suppression of liver metabolism, as a result of which kidney pathologies and intoxication of the body can develop. It is often prescribed together with anticoagulants, especially if a person has liver disorders.
It is a broad-spectrum antibiotic that is active against gram-positive and gram-negative microorganisms. It is usually prescribed at 500 mg per day (for an adult). Children under 12 years of age are not recommended to take amoxicillin, as it causes dysbacteriosis and can lead to metabolic and endocrine disorders.
- Ampicillin
It is considered as an analogue of Biseptol. It is prescribed for various forms of angina (most often for lacunar, follicular form). Ampicillin is recommended to be taken at 500 mg per day.
It is a good alternative to biseptol and other similar drugs. Amoxiclav is prescribed for the treatment of respiratory diseases, sore throat, cough, runny nose. The main condition for effectiveness is to prescribe it for the treatment of diseases of bacterial origin. It is not effective against viral diseases, like any other antibiotic. It is available in the form of tablets with a dosage of 500 mg. The daily dosage is one tablet per day, since this is a prolonged-release drug. Only 3 tablets are required for the course. It should be taken into account that the drug can cause dysbacteriosis, so it is often prescribed together with probiotics. It is prescribed with caution to people suffering from liver pathologies (it is better to take it together with hepatoprotectors).
Various throat sprays have a positive effect on tonsillitis. One of these is Ingalipt. It is prescribed for diseases of bacterial genesis, since it not only has an antibacterial effect, but also moisturizes the mucous membrane. Also, all sprays normalize the microflora, restore the mucous membranes. Coughing is significantly reduced, inflammation and redness go away. Indications for the use of Ingalipt are any forms of tonsillitis: catarrhal, follicular, lacunar, fibrinous. It is also recommended if there is a risk of complications, including diseases of the lower respiratory tract (bronchitis, pneumonia, tracheitis).
Reviews
If you analyze the reviews, you can see that positive ones prevail among them. Negative reviews are extremely rare, and are mainly observed only with improper use of the drug, and with exceeding the dosage. Biseptol for angina significantly alleviates the condition, quickly relieves pain and inflammation. In 2-3 days, the cough decreases, the lymph nodes decrease, hyperemia and swelling of the throat go away. It is used by both children and adults. A characteristic feature is that the drug acts quickly. Already in about 1-3 hours, a noticeable improvement in the condition is observed. Many feel healthy after a day. Full recovery usually occurs on the 5th day, this is the minimum course of treatment.
Attention!
To simplify the perception of information, this instruction for use of the drug "Biseptol for sore throat: how to take, dosages" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.