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Antibodies to a protein that enhances the bactericidal effect of neutrophils
Medical expert of the article
Last reviewed: 23.04.2024
Normally, antibodies to the protein that enhances the bactericidal effect of neutrophils are absent in the blood serum (using the method of indirect immunofluorescence). For the ELISA method, the separation point for IgG antibodies is 15 U / ml.
The protein, which enhances the bactericidal action of neutrophils, is a membrane protein of neutrophils and monocytes. Its main function is to bind endogenes of bacteria. Antibodies to this protein are most often found in Crohn's disease and ulcerative colitis. In some cases, antibodies to a protein that enhances the bactericidal effect of neutrophils can be detected in chronic infectious diseases of various etiologies.
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