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Antibodies to a protein that enhances the bactericidal action of neutrophils
Medical expert of the article
Last reviewed: 05.07.2025
Normally, antibodies to the protein that enhances the bactericidal action of neutrophils are absent in the blood serum (using the indirect immunofluorescence method). For the ELISA method, the cutoff point for IgG antibodies is 15 U/ml.
Neutrophil antibacterial protein is a membrane protein of neutrophils and monocytes. Its main function is to bind bacterial endotoxins. Antibodies to this protein are most often found in Crohn's disease and ulcerative colitis. In some cases, antibodies to neutrophil antibacterial protein can be detected in chronic infectious diseases of various etiologies.
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