
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Treatment of adnexitis with antibiotics
Medical expert of the article
Last reviewed: 04.07.2025
Treatment of adnexitis with antibiotics begins with intramuscular or intravenous administration of the drug, then replacement with tablets occurs.
Local use of antibacterial agents includes mainly rectal or vaginal suppositories, which help speed up the healing process, relieve inflammation and other unpleasant symptoms of the disease.
Tampons with Levomekol for adnexitis
Levomekol has antimicrobial, anti-inflammatory and healing effects due to its combined action. The drug has a detrimental effect on gram-negative bacteria that are resistant to antibiotics, Pseudomonas aeruginosa and Escherichia coli, staphylococci. In addition, Levomekol has an immunostimulating effect - it promotes the production of its own interferon. The ointment penetrates deeply into the tissue, without damaging the membranes, and has a powerful therapeutic effect. In the presence of purulent contents or a large amount of dead tissue, the therapeutic effect of the ointment does not decrease.
Treatment of adnexitis exclusively with tampons containing Levomekol is ineffective, so such treatment is often prescribed in combination therapy. Tampons containing Levomekol for inflammation of the appendages deliver the active substance to the tissues surrounding the vagina, i.e. the therapeutic effect is observed directly in the ovaries and fallopian tubes. The course of treatment is determined by the doctor and depends on the severity of the disease.
Azithromycin for adnexitis
Azithromycin is an antibiotic that actively acts in the inflammation focus and has a high bactericidal effect. Treatment of adnexitis is not carried out with azithromycin if the disease was caused by gram-positive bacteria, since they have pronounced resistance to this group of antibiotics.
The course of treatment is determined by the doctor, the drug must be taken two hours after meals or an hour before meals, usually 2 tablets per day are prescribed.
Doxycycline for adnexitis
Doxycycline is an antibiotic of the tetracycline series, which is active against many bacteria. The drug is available in capsules and is prescribed for inflammatory processes in the genitourinary organs, as well as for chlamydia, syphilis, etc. The dose and duration of treatment are determined by the doctor, the standard treatment regimen is: 2 capsules every 12 hours.
In addition to oral administration, intravenous administration of the drug is possible.
Treatment of adnexitis with the antibiotic doxycycline gives good results and relief comes in the first days.
[ 4 ]
Gentamicin for adnexitis
Gentamicin is a broad-spectrum antibiotic that quickly reaches the affected area and actively suppresses the proliferation of pathogenic microflora.
Treatment of adnexitis with gentamicin is carried out in combination with additional methods (physiotherapy, anti-inflammatory drugs, etc.). On average, the course of treatment with gentamicin lasts 7-10 days, the drug is administered intravenously 2 times a day. The drug is excreted from the body with urine, so gentamicin is not prescribed for renal failure.
Amoxiclav for adnexitis
Amoxiclav has a combined effect, a drug from the penicillin group with the addition of clavulanic acid, which blocks the ability of pathogenic microorganisms to develop resistance to the main active substance of the drug - amoxicillin. Before prescribing amoksiklav, it is necessary to conduct a test for the susceptibility of microorganisms, since the drug is effective only against bacteria sensitive to it.
Treatment of adnexitis is usually carried out according to the following principle: one tablet three times a day (every eight hours), in acute cases the dosage is increased, but no more than 6000 mg should be taken per day. Amoxiclav tablets should be dissolved in water or chewed and washed down with a sufficient amount of water before taking.
Intravenous administration of the drug is also possible.
Amoxicillin for adnexitis
Amoxicillin has a bactericidal effect. Treatment of adnexitis with amoxicillin is carried out taking into account the degree of susceptibility of the microorganisms that caused the disease and the severity of the disease, so the drug can only be taken as prescribed by a doctor.
[ 7 ]
Ceftriaxone for adnexitis
Ceftriaxone is a third-generation cephalosporin antibiotic. The drug is widely used to treat infectious diseases in gynecology.
Treatment of adnexitis with ceftriaxone is recommended when pathogenic vaginal microflora joins the inflammatory process, since in this case a broad-spectrum drug is needed. In some cases, treatment is combined with antibiotics of another group.
Ceftriaxone is administered intravenously or intramuscularly.
Ciprofloxacin for adnexitis
Ciprofloxacin of the fluoroquinolone group has a broad spectrum of action. The drug destroys not only active bacteria in the reproduction stage, but also those that are dormant.
Treatment of adnexitis is carried out if the inflammation is caused by mycobacterium tuberculosis, chlamydia, etc. Most staphylococci that have developed resistance to methicillin do not respond to ciprofloxacin.
Tsifran for adnexitis
The active ingredient of ciprofloxacin is ciprofloxacin from the fluoroquinolone group. The drug is active against most pathogenic microorganisms and is used to treat some systemic infections, diseases caused by anaerobic and aerobic microorganisms. Today, ciprofloxacin is one of the most frequently prescribed antibiotics of the fluoroquinolone group.
Treatment of adnexitis with tsifran is prescribed after analyzing the sensitivity of pathogenic flora to the active substance of the drug.
Tsifran is available in various forms: tablets, solutions for injections and droppers, as well as in the form of drops and ointments.
Polygynax for adnexitis
Anti-inflammatory vaginal suppositories with antibacterial action show good results in adnexitis, especially at the onset of the disease. When inserted, the suppositories melt under the influence of body temperature, as a result of which the active substance is absorbed by the mucous membrane rather slowly.
The most popular in the treatment of inflammation of the female genital organs is Polygynax, which is inserted into the vagina one capsule per day. The course of treatment is determined by the attending physician, but does not exceed two weeks. Treatment of adnexitis with Polygynax has several advantages. First of all, the drug does not penetrate the bloodstream and has virtually no contraindications.
Augmentin for adnexitis
Augmentin is a combination penicillin. The drug contains clavulanic acid, which disrupts the development of microorganism resistance to antibiotics, thereby significantly increasing its effectiveness. The main active ingredient of the drug is amoxicillin, which has a broad spectrum of action. Treatment of adnexitis with Augmentin is usually carried out in cases of infection after childbirth, abortion, ectopic pregnancy, gonorrheal, staphylococcal and other infections.
Nolitsin for adnexitis
Nolitsin is an antibiotic from the quinolone group, which is active against many bacteria. It has a pronounced antimicrobial effect. If the tests have revealed gram-negative, gram-positive (some types) microflora, Pseudomonas aeruginosa in the fallopian tubes, then treatment of adnexitis is prescribed using nolitsin. The drug destroys bacteria sensitive to it well, in addition, pathogenic microflora is practically unable to develop resistance to it.
Tsiprolet with adnexitis
Ciprolet is a fluoroquinolone antibiotic that is often used for infectious gynecological diseases. Treatment of adnexitis with ciprolet has shown fairly high efficiency and speed of action. The drug is especially effective against gram-negative microflora, but some gram-positive flora is also susceptible to it, for example, staphylococci. The drug is also prescribed for intracellular microorganisms (mycobacterium tuberculosis, chlamydia).
The drug has virtually no effect on anaerobic bacteria and treatment in this case will be ineffective.
Terzhinan for adnexitis
Terzhinan is a combination drug used locally for gynecological diseases. The components included in Terzhinan achieve a bactericidal, anti-inflammatory effect. The drug is available in the form of vaginal tablets and does not disturb the natural balance of the vaginal mucosa. Treatment of adnexitis with Terzhinan is indicated for inflammation caused by anaerobic infections, as well as trichomonads or mixed flora.
Sumamed for adnexitis
In acute inflammation of the appendages, antibiotics are prescribed immediately, i.e. without waiting for test results. In this case, doctors use antibiotics to which most pathogenic microorganisms are sensitive. Sumamed is a member of the macrolide group, which has a long period of action, due to which high concentrations of the substance accumulate in the lesion. The drug inhibits most pathogenic microorganisms that provoke inflammatory diseases. Treatment of adnexitis with the antibiotic sumamed shows high efficiency.