Sanguiritrin

The antimicrobial agent Sanguiritrin is a plant antiseptic that is produced from the herbaceous plant Macleaya of two species - heart-shaped and small-fruited, belonging to the poppy family. The antimicrobial drug is represented by a biosulfate complex of alkaloid substances chelerythrine and sanguinarine, related in structure and characteristics.

Indications Sanguiritrin

The antimicrobial drug Sanguiritrin can be used for therapeutic or prophylactic measures, in pediatrics or in adult patients, starting from the neonatal period. Sanguiritrin can be used as needed during pregnancy and after childbirth.

For preventive purposes, Sanguiritrin is used in newborn babies to prevent infectious lesions of the skin, as well as in patients with surgical pathology to prevent purulent and inflammatory processes in wounds.

For therapeutic purposes, Sanguiritrin is prescribed for infectious and inflammatory processes in skin and mucous tissues, both microbial and fungal in origin.

The drug can be used as an auxiliary agent in dental practice for periodontal inflammation, gingivitis and stomatitis, as well as other inflammatory processes of the oral mucosa.

Surgeons use Sanguiritrin to treat infected wound processes, burns, chronic wounds and ulcers.

Otolaryngologists use the drug to treat pathologies of the middle ear, or inflammation of the auricle and the outer part of the auditory canal.

Gynecologists can use Sanguiritrin to treat patients with erosion, vaginitis, colpitis, endocervicitis.

In dermatological practice, Sanguiritrin is used for purulent skin lesions and mycoses.

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Release form

Sanguiritrin is a 0.2% alcohol liquid, which is used exclusively for external procedures. The liquid has a rich orange hue and a characteristic alcohol smell.

The antiseptic consists of the active ingredient sanguiritrin and additional substances – ethyl alcohol and water.

The drug Sanguiritrin is poured into dark glass bottles, which are then placed in cardboard boxes. The kit includes an annotation to the antimicrobial agent.

Names of analogues of the drug Sanguiritrin

There are no equivalent analogues of the antimicrobial drug Sanguiritrin, but there are a number of drugs with a similar mechanism of action. We suggest you familiarize yourself with the list of drugs with similar action.

• Antisept - 70% external solution.
• Antiseptol - 70% external solution.
• Ascosept is an external drug.
• AHD 2000 is an external antimicrobial agent.
• Biosept 70 – solution.
• Vitasept 70% and 96% liquid.
• Vitafarm 70% and 96% external agent.
• Euraethyl 70% and 96% external agent.
• Megasept and Medasept are alcohol solutions.
• Septil – alcohol liquids 70% and 96%.
• Septosteril is an antiseptic for external use.
• Pharmasept – solution 96%.

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Pharmacodynamics

The antiseptic Sanguiritrin acts on a large number of pathogenic microbes, including gram (+) and gram (-) bacteria, yeast and mycelium. The drug is active against microbial strains resistant to most antibiotics.

Standard dosages of Sanguiritrin have a bacteriostatic effect – they stop the growth and reproduction of infection.

The essence of the antibacterial effect of the drug consists in the suppression of microbial nuclease, disruption of the mechanisms that ensure cellular permeability, metabolic processes within cells and disruption of the nucleotide structure.

Pharmacokinetics

There is no data on the penetration of the external antiseptic Sanguiritrin into the systemic bloodstream, therefore the kinetic properties of the drug cannot be described.

Dosing and administration

The antiseptic Sanguiritrin is used only as an external agent.

On the fifth or sixth day after the birth of the child, the preparation is applied to the skin folds, morning and evening.

In case of periodontal inflammation, cotton swabs with Sanguiritrin are placed in the gum pockets, holding them for about 20 minutes. To prepare a less concentrated aqueous solution of Sanguiritrin, mix 1 teaspoon of 0.2% alcohol solution and 200 ml of clean boiled water. Cotton swabs are inserted every day or once every two days. The general course of treatment involves 5-6 procedures.

For the treatment of stomatitis, application of Sanguiritrin is prescribed up to three times a day for 3-5 days. Older children can be recommended to rinse the mouth with a diluted solution. For small children under 5 years of age, the diluted preparation is applied directly to the mucous membrane.

To treat colds, tonsils are treated with 0.2% liquid at night for 3-4 days. Older children and adults can gargle with a warm diluted solution. Duration of treatment is up to 1 week.

In case of ear inflammation, cotton swabs soaked in 0.2% Sanguiritrin are inserted into the auditory canals and left for 15 minutes. The procedure is repeated up to 3 times a day. The duration of therapy is at least 14 days. If the inflammatory process is chronic, Sanguiritrin is dripped into the auditory canal 5-7 drops for an adult patient, and up to 2 drops for children.

To prevent wound complications, treat the wound with a gauze napkin soaked in 0.2% Sanguiritrin. You can leave a compress with an antiseptic under the bandage. The duration of treatment is determined by the doctor, depending on the healing of the wound surface. Most often, one week may be required for partial wound healing.

In the presence of infection in the wound, in case of sluggish, difficult-to-heal processes, diluted Sanguiritrin is used for rinsing and applying lotions.

For gynecological diseases, the diluted solution is used for douching, applications and baths. The procedures are carried out every day for 5 days, 1-2 times (for example, in the morning and evening).

For purulent skin diseases or dermatomycosis, 0.2% Sanguiritrin is used in the form of dressings or applications to the affected areas, up to 2 times a day. The duration of treatment is determined by the doctor.

Use Sanguiritrin during pregnancy

The antimicrobial agent Sanguiritrin is approved for external use in women during pregnancy. Treatment should be prescribed by a doctor and carried out under his supervision.

The use of the drug during breastfeeding is also not prohibited if there are appropriate indications.

Contraindications

The antimicrobial agent Sanguiritrin cannot be prescribed:

• patients suffering from epilepsy;
• in hyperkinesis;
• for bronchial asthma;
• in case of severe angina pectoris;
• in acute liver and kidney failure;
• for fungal skin lesions that are accompanied by signs of eczematization;
• if there is a high probability of developing an allergic reaction to the drug.

Side effects Sanguiritrin

External application of Sanguiritrin to the skin may be accompanied by redness and a transient burning sensation. It is also possible to develop an allergic reaction to the drug.

When using the antimicrobial agent Sanguiritrin on the mucous membranes of the oral cavity, a short-term bitter taste in the mouth may appear.

If a patient experiences such side effects, he is advised to use a solution of lower concentration.

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Overdose

With frequent or abundant use of the external drug Sanguiritrin, sometimes an increased manifestation of side effects is noted. If this happens, then the concentration of the antimicrobial agent should be reduced. If necessary, symptomatic treatment is carried out.

Interactions with other drugs

Sanguiritrin can be used in combination with various external medications, in particular with local anesthetic drugs (for example, Promecaine or Trimecaine).

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Storage conditions

The antiseptic Sanguiritrin is stored in dark places, out of reach of children, maintaining a temperature regime from +15 to +25°C.

Shelf life

The shelf life of the drug is up to 3 years, subject to proper storage conditions.

Sanguiritrin should not be used if its expiration date has passed, since by this time the drug loses its pharmacological activity.