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Hematologist, oncohematologist

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Protein fractions

Alexey Portnov, medical expert
Last reviewed: 19.11.2021

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For the separation of protein fractions, a method of electrophoresis is usually used, based on the different mobility of whey proteins in an electric field. This study is diagnostic more informative than the determination of only the total protein or albumin. On the other hand, the study of protein fractions makes it possible to judge the protein excess or deficiency characteristic of a disease only in its most general form. Analysis of the results of electrophoresis of proteins allows us to determine at the expense of which fraction the patient has an increase or decrease in the concentration of the total protein, and also to judge the specificity of the changes characteristic of this pathology.

Protein fractions of blood serum are normal

Fractions	Content,%
Prealbumins	2-7
Albumins	52-65
α ₁ -Globulins	2.5-5
α ₂ -Globulins	7-13
β-Globulins	8-14
γ-Globulins	12-22

trusted-source [1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13]

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