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Pigmentless nevus: causes, symptoms, diagnosis, treatment

Medical expert of the article

Dermatologist, oncodermatologist
, medical expert
Last reviewed: 07.07.2025

The basis of the non-pigmented nevus is a decrease in the activity of melanocytes. The number of the latter in the skin is normal. In the cytoplasm of melanocytes, the number of melanosomes is also normal, while in keratinocytes the number of melanosomes is reduced.

Symptoms of depigmented nevus. Dermatosis is congenital, occurs in all races and equally often in men and women. The disease is characterized by the appearance on the skin of the body, limbs of single (usually one), asymmetrically located, white spots of oval or round shape with clear, polycyclic boundaries. Depigmented nevus often occurs in childhood or, rarely, in adolescence and does not progress over time and does not disappear on its own (does not repigment).

There is no treatment for a non-pigmented nevus.

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