Pharmasept

Pharmasept is a disinfectant antiseptic drug.

Indications Pharmasept

The medicine is used as an antiseptic to disinfect the skin, in particular on the hands. In addition, it can be used for lotions, various compresses or rubdowns, and also as an antifoam in case of pulmonary edema.

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Release form

Alcohol solution 96% for external use. Available in 50 or 100 ml bottles.

Pharmacodynamics

When applied externally, the drug has a local irritant effect, as well as a tanning effect on the skin along with the mucous membranes. The active substance of the drug - ethyl alcohol - promotes protein coagulation, and in addition, it interacts with viruses and gram-positive, and in addition to them, gram-negative bacteria.

In case of internal intake of ethanol, its effect on the cells of the central nervous system (most of all on the cerebral cortex) begins. Since the inhibition processes are weakened, the excitement characteristic of alcohol intoxication occurs. The result of this can be suppression of the functional activity of the respiratory center, and in addition, a disorder in the work of the spinal cord, as well as the medulla oblongata. In case of inhalation use, a systemic effect can be observed.

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Pharmacokinetics

The antifoaming effect begins to develop 10-15 minutes after using the medicine, and the drug reaches its maximum medicinal effect after 1 hour.

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Dosing and administration

The medicine should be applied to the skin using cotton swabs or tampons. Other application features should be determined by the doctor, depending on the clinical picture observed in the patient.

In case of methyl alcohol intoxication, oral administration of 30% ethyl solution is prescribed. In addition, 5% ethyl solution can be administered intravenously in combination with sterile injection saline solution of sodium chloride.

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Use Pharmasept during pregnancy

Pregnant women are prohibited from using Pharmasept.

Contraindications

Contraindications include: acute inflammation of the mucous membranes and skin, hypersensitivity of the patient to ethyl alcohol, and age under 14. In the case of using the drug to eliminate pulmonary edema, conditional contraindications include uncontrolled pain in acute ischemic heart disease, as well as psychomotor agitation of the patient.

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Side effects Pharmasept

When using drugs locally, side effects of the body may include irritation of the mucous membranes or skin, as well as suppression of central nervous system functions.

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Overdose

In case of local application, overdose usually does not occur, but if irritation or redness appears on the area of skin treated with the drug, the use of the drug should be discontinued and the affected area should be washed with cold water.

Internal use may cause suppression of the respiratory center function. If the drug is used orally or intravenously in large doses, a person develops a coma. It has its own symptoms: sticky cold skin, decreased temperature, facial hyperemia, involuntary release of urine or feces, vomiting, pupils constrict (or dilate if respiratory disorders are more severe). In addition, there is a frequent but weak pulse rhythm, as well as a slow respiratory rhythm and horizontal nystagmus. Convulsions, suffocation with vomit, and laryngospasm may occur quite rarely. Mechanical suffocation can lead to respiratory arrest, as a result of which the functioning of the cardiovascular system may be disrupted.

In case of ethanol intoxication after oral administration, vomiting should be induced, followed by gastric lavage. In case of severe poisoning, resuscitation procedures are required.

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Interactions with other drugs

In case of combination of ethanol with nitrofurans, the toxic effect of the latter increases. When combined with oral antidiabetic drugs (aminophenolsulfonic acid derivatives), the patient may experience hypoglycemic coma. The use of Pharmacept with aspirin increases the possibility of developing a gastric ulcer, and when combined with thiamine, the properties of the latter are weakened.

The use of drugs simultaneously with sleeping pills may cause difficulty and suppression of the respiratory process. The neurotoxic effect of penicillins, cephalosporins, and fluoroquinolones in combination with Farmasept is enhanced.

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Storage conditions

The medicine should be kept in a tightly sealed package, away from open flames.

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Shelf life

Pharmasept has an unlimited shelf life.

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