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Pepsan
Medical expert of the article
Last reviewed: 04.07.2025
Pepsan is a member of the antacid subgroup of drugs, as well as combination substances of this type; it is used to reduce intestinal gas formation processes.
In addition, the drug helps protect the gastroduodenal mucosa. [ 1 ]
Its main active components are dimethicone with guaiazulene. Among the auxiliary elements of the drug are carrageenates with sorbitol, oil produced from peppermint, Na cyclamate, purified water, etc.
ATC classification
Active ingredients
Pharmacological group
Pharmachologic effect
Indications Pepsan
It is used in cases of pain associated with peptic ulcers, as well as other pains inside the esophagus and gastrointestinal tract (without reference to the etiology of these pains), including heartburn and increased pH levels.
Due to the absence of sugar in the composition of the medicine, it can be used by diabetics.
Release form
The drug is released in the form of a gel for oral use - 30 dosed packets inside a pack.
Pharmacodynamics
Dimethicone, which is the most common medicinal silicone, is used in gastroenterological processes (reduces foaming and bloating), and also has an absorbent and enveloping effect. The antacid activity of dimethicone allows it to protect the gastric mucosa.
Guaiazulene demonstrates regenerative, anti-inflammatory and antioxidant effects. It slows down the processes of histamine release through mastocyte-like cells of the gastric mucosa, reducing the rate of acid secretion. As a result, an antacid effect develops.
Dosing and administration
The medicine should be taken orally. One packet of the drug corresponds to 1 dosage. It is used before meals or in case of pain in the esophagus or stomach.
For 1 use, you should use 1-2 packets of the medicine. It can be used 2-3 times a day. It is necessary to completely use the entire contents of the dosed packet.
The duration of therapy is selected by the attending physician individually, taking into account the effectiveness of the medication and the intensity of developing symptoms.
It is prohibited to use in combination with other medications, because such administration may slow down their therapeutic activity.
- Application for children
The use of the medication by persons under 12 years of age is prohibited.
Use Pepsan during pregnancy
It is prohibited to prescribe Pepsan during pregnancy. It is used only in situations where it is considered that the benefit from its use is more likely than the risks of negative manifestations on the part of the fetus.
If there is a need to use the drug during breastfeeding, breastfeeding should be stopped for the duration of therapy.
Contraindications
Contraindicated for use in people with severe intolerance to any of the components of the medication.
The drug should not be used in combination with substances that contain Al hydroxide or Mg carbonate, because they weaken the antifoaming effect of the drug.
Side effects Pepsan
When administering Pepsan, a decrease in blood phosphorus levels may be observed.
If any unusual negative symptoms appear after taking the medicine, you should consult with your doctor regarding a possible change in the treatment course.
Overdose
The probability of intoxication is very low – this is due to poor gastric absorption of the drug’s components.
In case of poisoning, it is necessary to immediately perform gastric lavage, take enterosorbents and carry out other symptomatic actions.
Interactions with other drugs
The antifoaming effect of the drug is weakened by the action of Mg carbonate and Al hydroxide.
Storage conditions
Pepsan should be stored in a place closed to small children and moisture penetration. Temperature values are no more than 25°C.
Shelf life
Pepsan can be used for a period of 24 months from the date of sale of the therapeutic agent.
Analogues
Analogues of the drug are Digel, Trivin with Almagel neo, Manti and Contracid.
Attention!
To simplify the perception of information, this instruction for use of the drug "Pepsan" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.
Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.