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Lymphomas
Medical expert of the article
Last reviewed: 04.07.2025
Lymphomas are a heterogeneous group of neoplastic diseases originating from the reticuloendothelial and lymphatic systems. The main types of lymphomas are Hodgkin lymphoma and non-Hodgkin lymphomas.
Lymphomas were once considered to be diseases completely different from leukemia. However, a better understanding of cell markers and mechanisms of their evolution has shown that the differences between these two nosological forms are often absent. The idea that lymphoma is relatively limited to the lymphatic system, and leukemia to the bone marrow, is also not always true.
Comparison of Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma
Hodgkin's lymphoma |
Non-Hodgkin's lymphoma |
Localized in a specific group of lymph nodes |
Dissemination in more than one group of lymph nodes is typical. |
Orderly spread, usually into adjacent areas |
The distribution is disordered |
As a rule, it does not affect Waldeyer's rings and mesenteric lymph nodes |
Usually affects mesenteric lymph nodes and may involve Waldeyer's ring |
Extranodal lesions are not typical |
Extranodal areas are often affected |
Usually diagnosed in the early stages |
As a rule, it is diagnosed at a widespread stage. |
Favorable histological variants are more often detected in children |
In children, high-grade malignant variants are usually detected |
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