Lasolvan for coughing

The mucoregulatory drug Lazolvan for cough (ATC code R05CB06) is also included in the numerous pharmacological group of expectorants – secretolytics and stimulants of respiratory tract motility.

Indications Lasolvan

Indications for the use of Lazolvan include: acute respiratory viral infections and acute respiratory infections, acute and chronic forms of bronchitis, asthmatic bronchitis, pneumonia, bronchiectatic and chronic obstructive pulmonary disease. [ 1 ], [ 2 ]

Answering the question – what kind of cough is Lazolvan prescribed for? – experts emphasize its effectiveness in productive cough, that is, accompanied by the production of bronchopulmonary surfactant (secretions or sputum), which is difficult to cough up due to its viscosity. Thus, to liquefy thick sputum and facilitate its removal, Lazolvan should be used for wet cough.

Lazolvan is not indicated for allergic cough, as well as for dry cough: first, it is recommended to use remedies for dry cough - so that the cough becomes productive.

Release form

Pharmaceutical companies produce: Lazolvan cough syrup (in 100 ml bottles; concentration for adults - 30 mg/5 ml, for children - 15 mg/5 ml); Lazolvan cough tablets of 30 mg (in blisters of 10 pieces); Lazolvan cough lozenges (for dissolving in the mouth); infusion solution (in 2 ml ampoules with a concentration of 7.5 mg/ml).

Lazolvan solution is also used for inhalation for coughs with difficult to remove sputum, read - Lazolvan for inhalation for coughs;

The cough mixture Lazolvan is not produced.

Pharmacodynamics

The mucoregulatory mechanism of action of this drug is provided by its active substance - ambroxol hydrochloride, which increases the amount of sputum and simultaneously reduces its viscosity, facilitating coughing. [ 3 ], [ 4 ] See the instructions for the drug Lazolvan

Pharmacokinetics

All details are in the instructions for the drug Lazolvan.

Dosing and administration

Lazolvan tablets (orally, one tablet three times a day) are prescribed to adult patients and children over 12 years of age.

For this same category of patients, Lazolvan lozenges are intended (for the first two days, dissolve one lozenge no more than six times a day, then no more than four times).

Lazolvan syrup is taken by adults and adolescents in a single dose of 10 ml (two to three times during the day). Children aged 6-12 years take 5 ml of syrup, and children aged 2-5 years take 2.5 ml up to three times a day; the same amount of syrup (1/2 teaspoon) is given to children under two years old, but twice a day.

The maximum duration of use of Lazolvan is five days. [ 5 ]

How to use a nebulizer with Lazolvan for cough, read - Inhalations for bronchitis with a nebulizer.

Application for children

Children under six years of age are prescribed Lazolvan in syrup form. Tablets and lozenges are only permitted for use after six years of age.

In cases of respiratory failure in newborns and premature babies, Lazolvan solution is used for infusions in order to increase the synthesis of surfactant lining the alveoli of the lungs.

Use Lasolvan during pregnancy

According to the instructions, it is not recommended to use Lazolvan in the first trimester of pregnancy.

Contraindications

Lazolvan is not used in cases of individual hypersensitivity to ambroxol hydrochloride, in patients with renal insufficiency and during lactation.

Side effects Lasolvan

Possible side effects of Lazolvan include allergic reactions (including on the skin), heartburn and stomach pain, as well as nausea and vomiting.

Overdose

In cases of overdose, nausea, vomiting and diarrhea occur. It is necessary to wash the stomach within the first two hours after the appearance of these symptoms. Symptomatic treatment is then carried out.

Interactions with other drugs

Lazolvan should not be taken simultaneously with drugs that suppress the cough reflex.

It should also be borne in mind that ambroxol hydrochloride promotes the concentration of a number of antibiotics (Erythromycin, tetracycline and penicillin group drugs) in bronchial secretions.

Storage conditions

The optimal storage conditions for Lazolvan syrup and inhalation solution are at a temperature of +10-25°C; infusion solution – at a temperature of +10-18°C; tablets and lozenges – up to +28°C.

Shelf life

The shelf life of tablets, lozenges and solutions is five years; syrup – no more than three years.

Frequently asked questions

1. Can Lazolvan make cough worse? If Lazolvan makes cough worse, the reason is most often associated with a violation of the motor function of the ciliated epithelium of the bronchi.
2. Is it possible that Lazolvan has no therapeutic effect? If Lazolvan does not help with cough, then obviously the drug is used for dry cough – when phlegm is not formed, or the cough is reflexive.
3. What is better for cough Ambrobene or Lazolvan? Ambrobene and Lazolvan are synonyms, these are different trade names of drugs based on the same active substance (ambroxol hydrochloride). With this substance, drugs are produced that have trade names: Ambroxol, Ambrogeksal, Ambrosan, Ambrolitik, Bronchopront, Bronkhoksol, Viskomcil, Linloxil, Mukosol, Mukosan, Mukofar, Medox, Flavamed, Fluixol, Halixol.
4. Lazolvan or Erespal - which is better for cough? Erespal, which contains the antihistamine and bronchodilator fenspiride hydrochloride, is not an expectorant. Erespal reduces the synthesis of bronchial secretions in case of bronchospasm, respiratory failure in chronic bronchitis and cough associated with bronchial asthma.
5. What can replace Lazolvan? Lazolvan analogues are cough mixtures of various compositions that thin phlegm. For more details, see - Effective expectorants for bronchitis.