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Hypochloremic coma - Symptoms

Medical expert of the article

Gastroenterologist
, medical expert
Last reviewed: 06.07.2025

In most patients, coma develops gradually, most often after prolonged vomiting, diarrhea, and copious diuresis (depending on the underlying disease). In the pre-comatose state, severe weakness, dizziness, severe thirst, dry mouth, palpitations, muscle twitching, and often cramps in the calf muscles are disturbing.

Coma is characterized by the following signs:

  • pointed facial features, sunken eyes, haggard face;
  • pronounced dryness of the skin, decreased turgor and elasticity;
  • dry tongue, mucous membrane of the oral cavity, dry cracked lips covered with brownish crusts;
  • pupils are wide;
  • muscle twitching, often convulsions (with hypocalcemia);
  • decreased tendon reflexes;
  • the pulse is frequent and small;
  • blood pressure is significantly reduced;
  • When examining the abdomen, gastric peristalsis can be seen (with pyloric stenosis), and when palpated, a splashing sound and a low location of the stomach border can be detected;
  • In severe cases of coma, especially if treatment is not active enough or started late, acute renal failure may develop.

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