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Hepatitis B test: IgG antibodies to HBcAg (Anti-HBc IgG) in blood
Medical expert of the article
Last reviewed: 04.07.2025
Anti-HB with IgG are normally absent in the blood serum.
In patients, anti-HB with IgG appear in the acute period of viral hepatitis B and persist throughout life. Anti-HB with IgG is the leading marker of previous viral hepatitis B.
Blood testing for the presence of anti-HB c IgG is used for the following purposes:
- diagnostics of chronic HBV carriage in the presence of HB s Ag in the blood serum;
- diagnostics of previous viral hepatitis B.
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