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Fusariums - pathogens of fusariosis

Medical expert of the article

Internist infectious disease
, medical expert
Last reviewed: 23.04.2024

Fusarium is caused by septic mold fungi of the genus Fusarium.

Fusariums - pathogens of fusariosis

trusted-source[1], [2], [3], [4], [5], [6], [7]

Morphology and physiology of fusarium

Fungi of the genus Fusarium form a well-developed mycelium of white, pink or red color. There are microconidia, macroconidia, rarely chlamydospores. Macroconidia multicellular fusiform-falcate. Microconidia oval pyriform. They grow on Czapek's medium in the form of fluffy colonies.

Pathogenesis and symptoms of fusariosis

Mushrooms are widespread, especially on plants. In persons with immunodeficiency, fungi can affect the skin, nails, cornea and other tissues (F. Moniliforme, F. Sporotrichiella, F. Anthapitum, F. Chlantydosporum). Develop a fever, there are rashes. Foci of lesion are localized mainly on the limbs.

At low temperatures, F. Sporotrichiella, producing mycotoxin, develops on cereals. The use of such cereals, which overwintered under snow, causes mycotoxicosis. Mycotoxicoses are also caused by the use of grain products. There is a defeat of the central nervous system with a violation of coordination of movements.

Microbiological diagnosis of fusariosis

Explore nails, skin, subcutaneous tissue, cornea, blood, the tip of the permanent catheter, vomit, feces, tissue biopsy. Isolate the fungi and determine their toxins. Apply RIF. On nutrient media grow fluffy or cotton-like colonies of white color, which as they grow older become lilac-blue, pink-red, yellow or green. Fungi form a mycelium, micro- and macroconidia. Old cultures can form chlamydospores. Sometimes put PTSR.

Treatment of fusariosis

Fusariosis is treated with the use of amphotericin B, new triazoles (voriconazole or posaconazole).


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