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Hematologist, oncohematologist

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Evaluation of the results of the analysis of mucus from the nose

Alexey Portnov, medical expert
Last reviewed: 23.04.2024

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Assessment of the degree of activity of an allergic reaction according to the results of a study of scrapings from the nasal mucosa

Activity of an allergic reaction	Number of eosinophils and neutrophils	The number of basophils and mast cells
Absent (-)	0-1	0-0.3
Weak (+)	1.1-5	0.4-1
Average (++)	6-15	1.1-3
High (+++)	16-20	3.1-6
Very high (++++)	More than 20	More than 6

Changes in scrapings from the nasal mucosa and a presumptive diagnosis

Symptom	Presumptive diagnosis
Increase in the number of eosinophils	Allergic rhinitis, eosinophilic non-allergic rhinitis, rhinitis with intolerance to acetylsalicylic acid, Cherdja Strauss syndrome, nasal polyps
Increase in the number of basophils and mast cells	The same (in the presence of eosinophils) and systemic mastocytosis
An increase in the number of neutrophils:
With phagocytosed bacteria	Infectious rhinitis or nasopharyngitis
Without bacteria	Acute respiratory diseases, vasomotor rhinitis, rhinitis and sinusitis caused by irritants, allergic rhinitis (the latter is accompanied by eosinophilia)
Cages of ciliated epithelium with condensed chromatin	Acute respiratory diseases
Increase in the number of goblet cells	Allergic or infectious rhinitis (less often - vasomotor rhinitis)

Similarly, the results of scrapings from the conjunctiva in allergic eye diseases are examined and evaluated. An increase in the number of eosinophils, basophils and mast cells is evidence in favor of allergic conjunctivitis; prevalence of neutrophils - about bacterial conjunctivitis, conjunctivitis caused by irritants (in combination with an increase in the content of eosinophils - allergic conjunctivitis); lymphocytes - about viral conjunctivitis.

trusted-source [1], [2], [3], [4], [5], [6], [7]

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