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Evaluation of nasal mucus test results

Medical expert of the article

Hematologist, oncohematologist
, medical expert
Last reviewed: 06.07.2025

Assessment of the degree of activity of an allergic reaction based on the results of a study of scrapings from the nasal mucosa

Activity of allergic reaction

Eosinophil and neutrophil counts

Basophil and mast cell count

Absent (-)

0-1

0-0.3

Weak (+)

1,1-5

0.4-1

Average (++)

6-15

1,1-3

High (+++)

16-20

3.1-6

Very high (++++)

More than 20

More than 6

Changes in nasal mucosa scrapings and presumptive diagnosis

Sign

Presumptive diagnosis

Increased eosinophil count

Allergic rhinitis, eosinophilic nonallergic rhinitis, rhinitis due to intolerance to acetylsalicylic acid, Churg-Strauss syndrome, nasal polyps

Increased number of basophils and mast cells

The same (in the presence of eosinophils) and systemic mastocytosis

Increased neutrophil count:

With phagocytized bacteria

Infectious rhinitis or nasopharyngitis

No bacteria

Acute respiratory diseases, vasomotor rhinitis, rhinitis and sinusitis caused by irritants, allergic rhinitis (the latter is accompanied by eosinophilia)

Ciliated epithelial cells with condensed chromatin

Acute respiratory diseases

Increased number of goblet cells

Allergic or infectious rhinitis (less often - vasomotor rhinitis)

The results of conjunctival scrapings are examined and assessed in a similar manner in allergic eye diseases. An increase in the number of eosinophils, basophils and mast cells indicates allergic conjunctivitis; the predominance of neutrophils indicates bacterial conjunctivitis, conjunctivitis caused by irritants (in combination with an increase in the content of eosinophils - allergic conjunctivitis); lymphocytes - viral conjunctivitis.

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