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Diagnosis of intestinal yersiniosis
Medical expert of the article
Last reviewed: 23.04.2024
Of the clinical symptoms, the most important is the lesion of the gastrointestinal tract (diarrhea) followed by the appearance of a polymorphous rash in the patient, mainly on the hands, feet, around the joints, enlargement of the liver, spleen, arthralgia, nodular eruptions and other characteristic signs of the disease (prolonged fever, changes in the kidneys, heart , peripheral blood, etc.).
For laboratory diagnostics PCR and bacteriological method are of the greatest importance. Y. Enterocolitica can be isolated from feces, blood, urine, pus, mucus from the throat, lymph nodes, surgical material, etc. Most often the pathogen is excreted in the first 2-3 weeks from the onset of the disease, sometimes it can be released up to 4 months. With the joint and cutaneous forms of the pathogen is very rare. Serologic diagnostics are used in these cases. They put RA with the living or dead culture of Yersinia and RNGA in the dynamics of the disease. Diagnostic titres in RA 1: 40-1: 160, in the RNGA - 1: 100-1: 200. The maximum titres of agglutinins decrease within 2 months.
Differential diagnostics
Intestinal yersiniosis should be differentiated firstly with scarlet fever, measles, enterovirus infection, rheumatism, sepsis, typhoid-like diseases.
Clinically differentiate intestinal yersiniosis with pseudotuberculosis in most cases is not possible, and only the use of laboratory methods (isolation of the pathogen, immunological responses) allows you to clarify the diagnosis of the disease.
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