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Health

Dalfusin

, medical expert
Last reviewed: 23.04.2024
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Dalfusin is used to increase the prostate gland. 

Indications Dalfusin

Dalfuzin is prescribed for benign education in the prostate gland. 

Release form

Dalfusin is available in the form of coated tablets.

Pharmacodynamics

Dalfuzin selectively blocks adrenoreceptor alpha 1 in the urethra, prostate gland, bladder, removes spasms, reduces internal pressure, thereby improving urination.

The medication corrects the urodynamic parameters: it reduces the tension in the urethra, the resistance to urine outflow, facilitates the process of urination and bladder release.

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Pharmacokinetics

Dalfusin is well absorbed in the digestive tract. The maximum value of the active substance reaches in the blood on average after three hours.

About 90% of the drug binds to blood proteins. Half-life from the body is about 8 hours, 11% of the active substance (alfusose) is excreted by the kidneys, splitting occurs mainly in the liver, most of the medicament is excreted with feces in the form of inactive metabolites.

In the elderly, there is a higher concentration of the active substance in the blood plasma and the bioavailability of the drug, the half-life remains the same.

With renal failure, the rates of excretion of the active substance from the body and the volume of distribution increase. In severe forms of renal failure, the drug does not accumulate in the body due to enhanced biotransformation. 

Dosing and administration

Dalfuzin is prescribed to adult patients 5 mg (1 tablet) twice a day. Medication should be taken after meals, tablets are not recommended to chew or break. Treatment is best to begin with an evening reception.

In old age, with renal failure, when taking drugs to increase blood pressure, is prescribed at 5 mg in the evening (if necessary, the doctor can increase the dosage to two tablets a day).

In a day is not recommended to take more than 10 mg of the drug.


 

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Use Dalfusin during pregnancy

Dalfuzin is not prescribed to pregnant women. Studies on the safety of the drug during this period was not conducted. 

Contraindications

Dalfusin is contraindicated in cases of increased susceptibility of the organism to certain components of the drug, reduced arterial pressure, liver failure, and also during the administration of other adrenoblockers of the alpha 1 receptors.

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Side effects Dalfusin

Dalfuzin can provoke headaches, tinnitus, weakness. In rare cases, fainting, drowsiness, and neuropsychiatric weakness are observed.

Also, the medication leads to a decrease in blood pressure, abnormal or rapid heart rate, with ischemic disease, exacerbation of symptoms of angina may occur.

In some cases, pain in the chest, swelling, rashes on the skin, itching, a feeling of nausea, upset of the stool, stomach pain, a feeling of dryness in the mouth. 

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Overdose

Dalfuzin in case of taking in excess of the recommended dose leads to a decrease in pressure. Treatment in case of an overdose of the drug symptomatic (the introduction of vasoconstrictor drugs, solutions of high molecular substances, etc.). Artificial purification of blood in this case is ineffective. 

Interactions with other drugs

Dalfuzin can not be used concomitantly with other adrenoblockers alpha 1. The drug enhances the effect of drugs that are prescribed with reduced blood pressure and means for anesthesia.  

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Storage conditions

Dalfusin should be kept closed dry in a place that does not penetrate sunlight. Storage temperature should not exceed 25 ° C. The medicine is stored in a place remote from small children. 

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Shelf life

Dalfuzin is suitable for two years from the date of production. 

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Attention!

To simplify the perception of information, this instruction for use of the drug "Dalfusin" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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