Cyclomed

Cyclomed has a cholinolytic and mydriatic effect. The drug is an m-cholinergic blocker, it blocks the activity of m-cholinergic receptors.

The use of the drug leads to an increase in the size of the pupil of the eye - this occurs due to the contraction of the pupil dilating muscle, and in addition to this, with the relaxation of the antagonist muscle. Along with this, the ciliary muscle also relaxes, which provokes the development of accommodative paresis. [ 1 ]

Indications Cyclomed

It is used during ophthalmoscopy procedures, as well as during refractive examination.

May be prescribed before cataract surgery to increase pupil size.

It is used in the combined treatment of inflammatory lesions of the anterior region of the eye ( episcleritis with iridocyclitis, uveitis and scleritis with keratitis).

Release form

The therapeutic substance is released in the form of 1% eye drops - inside dropper bottles with a volume of 5 ml. There is 1 such bottle inside the box.

Pharmacodynamics

Pupil dilation occurs 15-25 minutes after instillation; the effect lasts for 7-11 hours from the moment of application (sometimes even longer). Residual symptoms may also persist for up to 24 hours.

The drug has a weak antispasmodic effect, and in addition, it increases the IOP and reduces the tone of the vagus nerve, resulting in an increase in the heart rate (the pressure increases slightly). In addition, a deterioration in the excretory function of the salivary, gastric and bronchial glands, as well as the pancreas, may be noted.

Cyclomed overcomes the blood-brain barrier, when used in standard doses it stimulates brain activity, and also has a stimulating effect on the respiratory center.

Dosing and administration

The drops are intended for local use - they need to be instilled into the eyes, 1-2 drops in the area behind the eyelid.

To diagnose lesions in the fundus area, you need to instill 1-3 drops of the medicine - 1 drop at 10-minute intervals.

To perform a refractory study in a child, it is necessary to instill 2 drops of the substance at 15-17 minute intervals, no more than 3 times per day.

In case of eye inflammation, you need to drip 1 drop of Cyclomed 3 times a day.

• Application for children

The medication is not prescribed to children under 3 years of age.

Use Cyclomed during pregnancy

The use of the medicine during pregnancy and breastfeeding is permitted only with the prescription of the attending physician.

Contraindications

Main contraindications:

• trauma-related paresis affecting the muscle that contracts the pupil of the eye;
• glaucoma;
• severe intolerance to the components of the medication.

The medication should be used with great caution in cases of intestinal obstruction and prostate hyperplasia, as well as for the treatment of elderly people.

Side effects Cyclomed

Side effects include:

• eye lesions: temporary loss of visual acuity, conjunctival hyperemia and discomfort. In people with primary glaucoma, IOP may increase;
• systemic manifestations: dizziness, tachycardia, nausea and weakness.

Overdose

Overdose causes dryness in the epidermis and mucous membranes, as well as tachycardia and mental manifestations (disorientation, fatigue, emotional lability, incoherence). The introduction of large doses causes respiratory arrest and a comatose state.

Physostigmine must be administered intravenously (for an adult, the dose is 2 mg, and for a child, 500 mcg).

Interactions with other drugs

The medicinal effect of Cyclomed is reduced when using m-cholinomimetics. Its therapeutic effect is potentiated when combined with sympathomimetics.

Storage conditions

Cyclomed should be stored in a place closed to small children. The temperature level should not exceed 25°C.

Shelf life

Cyclomed can be used for a period of 2 years from the date of production of the pharmaceutical substance.

Analogues

The analogs of the drug are the medications Tropicamide and Mydriacil with Unitropic.

Reviews

Cyclomed is usually used for premedication before performing ophthalmological diagnostic procedures. Reviews rarely mention the appearance of negative symptoms when using the drops.