All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Common metanephryls in the urine
Medical expert of the article
Last reviewed: 23.04.2024
The reference values (norm) of excretion in the urine of common metanephrine are 2-345 mcg / day.
Common metanephrins are intermediate products of adrenaline metabolism. 55% of the adrenaline metabolism products are excreted in the urine in the form of metanephrine. A significant increase in the content of metanephrine in the urine is revealed in patients with pheochromocytoma, neuroblastoma (in children), ganglioneuropathy. The study is prescribed together with the definition of epinephrine and norepinephrine in urine in order to increase the likelihood of diagnosing the listed diseases.
For the diagnosis of pheochromocytoma, it is better to study the concentration of metanephrine in a single dose of urine obtained immediately after an attack of arterial hypertension. False positive results are possible in patients receiving chlorpromazine, benzodiazepines or sympathomimetics.
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12]