х
All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.
We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.
If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.
Causes of high and low testosterone
Medical expert of the article
Alexey Kryvenko, Medical Reviewer, Editor
Last reviewed: 06.07.2025
Last reviewed: 06.07.2025
Diseases and conditions in which serum testosterone concentrations change
Testosterone is elevated in the following conditions:
- Uremia.
- Myotonic dystrophy.
- Liver failure.
- Klinefelter syndrome.
- Cryptorchidism.
- Primary and secondary hypogonadism.
- Kallmann syndrome.
- Use of barbiturates, clomiphene, estrogens, gonadotropin, oral contraceptives.
- Idiopathic hirsutism.
Testosterone is reduced in the following conditions:
- Men with XYY karyotype.
- Stein-Leventhal syndrome.
- Feminizing testicle syndrome.
- Precocious puberty in boys.
- Virilizing luteoma.
- Tumors of the adrenal cortex.
- Extragonadal tumors in men, arrhenoblastoma.
- Use of androgens, dexamethasone, diethylstilbestrol, digoxin, ethanol, halothane, spironolactone, phenothiazines.
- Free testosterone in serum.
[