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Health

Calcium Gopantate

, medical expert
Last reviewed: 10.08.2022
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Calcium Gopantenate is a nootropic psychostimulating drug.

Indications of the calcium Gentate

It is used for combined treatment in such cases:

  • disorders of the cognitive type that developed as a result of cerebrovascular lesions of the organic type (among such complications after neuroinfection or CCT);
  • The central nervous system, provoked by changes in the atherosclerotic type in the region of the cerebrospinal vessels;
  • extrapyramidal disorders (such as progressive myoclonus, Huntington's chorea, hepatocerebral dystrophy and tremor paralysis);
  • epilepsy, in which inhibition of mental reactions is observed (treatment is performed in combination with anticonvulsants);
  • overloading of the psychoemotional type, weakening of working capacity, both physical and mental (helps to increase attention and concentration, and improve memorization);
  • neurogenic disorders of the urinary processes: such as pollakiuria with enuresis, and in addition urinary incontinence (imperative form) and urgency of imperative type;
  • children over 3 years of age with encephalopathy perinatal type and mental retardation with varying degrees of severity. In addition, children with developmental delays (verbal and psychic, motor, or a combination of these types), as well as with different forms of cerebral palsy, and in addition to ADHD (and with tics), stuttering (mostly clonic type) and in neurosis-like states.

trusted-source[1], [2], [3], [4], [5], [6]

Release form

The release is carried out in tablets, 50 pieces inside the can. In the package - 1 jar with tablets.

trusted-source[7], [8], [9]

Pharmacodynamics

The drug is affected by gopantenic acid, which affects the activity of the channel complex for the GABA-B receptor. The drug has anticonvulsant and nootropic properties. Increases brain resistance against hypoxia, as well as the effects of toxic elements, and in addition promotes the development of anabolic processes within neurons. The drug also combines a mild stimulating and sedative effect of a moderate type, reduces motor agitation and has an anticonvulsant effect.

It improves physical and mental performance, helps stabilize GABA in case of development of alcoholic poisoning of a chronic type, and also after the subsequent abolition of the use of ethyl alcohol. Extends the effect of sulfonamides with novocaine, slowing the reaction of acetylation of these substances. It contributes to retardation of pathologically intensified visceral reflex and detrusor tone.

trusted-source[10], [11], [12], [13]

Pharmacokinetics

The drug is rapidly absorbed from the gastrointestinal tract, passes through the BBB. In high concentrations found inside the skin, as well as kidneys with liver. To achieve peak performance, the drug takes 1 hour.

The medicine is not subjected to metabolic processes and is excreted unchanged after 48 hours: with urine output about 67.5%, and with faeces another 28.5%.

trusted-source[14], [15], [16], [17], [18]

Dosing and administration

Calcium preparation Gopantenate is used for combined treatment. Take the pill 15-30 minutes after eating.

The size of a single dose for adolescents over 12 years and adults is 0.25-1 g. Children within 3-12 years can take 0.25-0.5 grams of LS.

During the day adults and adolescents from 12 years old can take no more than 1.5-3 grams of the drug. Children aged 3-12 years can consume within a day within 0.75-3 grams of drugs.

The therapeutic course lasts from 1 to 4 months, sometimes up to six months. After 3-6 months after the first course, re-therapy is permitted.

To eliminate complications that have arisen because of neuroinfections or TBI: take 0.25 g of drugs (3-4 doses per day) - for adults and children over 3 years old.

For treatment of DVB: adults are prescribed 0.25 g, taken 3-4 times per day.

When eliminating extrapyramidal disorders, provoked by the use of neuroleptics: for adults, as well as adolescents from 12 years of age - taking 0.5-1 g three times a day. For children in the age range of 3-12 years - 3-4 times a day for 0.25-0.5 g of medication. This course lasts for 1-3 months.

During the treatment of epilepsy the drug is used in combination with anticonvulsants: for children aged 3-12 years - a dosage of 0.25-0.5 g, which is taken 3-4 times per day. To adolescents from 12 years old, and also to adults - the dosage is 0.5-1 g LS with reception 3-4 times a day. Tablets are used every day for a long course - up to six months.

To eliminate overloads of psychoemotional type, as well as deterioration of physical or mental performance: for children older than 3 years and adults - take three times a day for 0.25 g of drugs.

For the treatment of problems with the urinary function: adolescents aged 12 years and adults - taking 2-3 times per day, 0.5-1 grams of medication. Children within the age of 3-12 years - 2-3 times a day to use 0.25-0.5 grams of the drug (the size of the daily portion is 25-50 mg / kg). This course lasts for 1-3 months.

Children within the age of 3-12 years during the treatment of mental retardation, encephalopathy perinatal type, and in addition to cerebral palsy and developmental delay, it is required to take 0.5 g of the drug every day for 4-6 times. This course should last 3 months. During treatment, delays in speech development require 3-4 times a day to consume 0.5 grams of drugs over a period of 2-3 months.

When eliminating tics, ADHD with stuttering, and also neurotic-like conditions, a drug for children within 3-12 years of age is prescribed in the amount of 0.25-0.5 g for 3-6 doses per day for 1-4 months. Adolescents from 12 years old, as well as adults, should take 1.5-3 g per day for 1-5 months.

Scheme of drug use: increase dosage in the period of 7-12 days, then use the maximum portion for 15-40 days, followed by a gradual decrease in dosage until complete withdrawal of drugs for 7-8 days. The gap between treatment courses lasts 1-3 months.

trusted-source[33], [34], [35], [36], [37], [38], [39], [40]

Use of the calcium Gentate during pregnancy

It is forbidden to appoint in the 1st trimester. There is a possibility of use on the 2nd and 3rd trimesters, but only in cases where the likely benefits for a pregnant woman will be higher than the possibility of complications in the fetus.

Contraindications

Among the contraindications:

  • hypersensitivity to medicinal components;
  • acute renal pathologies in severe degree;
  • lactation period;
  • children under the age of 3 years.

trusted-source[19], [20], [21], [22], [23], [24], [25], [26]

Side effects of the calcium Gentate

The drug has a weak toxicity and is well tolerated. Among the possible side effects are allergy symptoms, such as rashes on the skin, conjunctivitis or runny nose. If the patient is allergic, it is necessary to cancel the drug intake.

trusted-source[27], [28], [29], [30], [31], [32]

Overdose

With intoxication, potentiation of side effects is observed.

To eliminate the overdose, it is required to take activated charcoal, perform gastric lavage, and perform symptomatic treatment.

trusted-source[41], [42], [43], [44], [45], [46], [47], [48]

Interactions with other drugs

The drug prolongs the effect of barbiturates, potentiates the properties of anticonvulsants, as well as drugs that have a stimulating effect on the central nervous system. Also, calcium hydroxide prevents the side effects of carbamazepine with phenobarbital, and in addition to neuroleptics. Together with this, he potentiates the properties of local anesthetics (such as procaine).

The drug can slow down the processes of acetylation, which are involved in the inactivation of novocaine, as well as sulfonamides, resulting in prolonged exposure to these drugs.

The properties of gopanthenic acid are potentiated when combined with etidronic acid and glycine.

trusted-source[49], [50], [51]

Storage conditions

Calcium gopantenate must be kept in a place inaccessible to children, with temperature readings not exceeding 25 ° C.

trusted-source[52], [53], [54], [55], [56], [57]

Special instructions

Reviews

Calcium gopentenate is usually intended for use in children and is considered to be quite effective in treating them. The testimonies indicate that after the application of drugs in children, in some cases, there are signs of withdrawal syndrome, which are observed in the form of a feeling of weakness.

trusted-source[58], [59], [60], [61], [62], [63], [64]

Shelf life

Calcium gopantenate can be used in the period of 3 years from the date of release of the drug.

trusted-source[65], [66], [67], [68], [69]

Attention!

To simplify the perception of information, this instruction for use of the drug "Calcium Gopantate" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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