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Berylliosis of the skin
Last reviewed: 23.04.2024
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Berylliosis is a systemic occupational disease with primary respiratory damage, which is based on the formation of typical immune granulomas from the introduction of metals. Beryllium granulomas in the skin develop as a result of ingress of beryllium through damaged skin, less often - hematogenous. Clinically, the lesions have the appearance of small or large-scale, cyanotic or yellowish-red formations, similar to those in sarcoidosis. There may be ulceration. Skin tests with beryllium are usually sharply positive.
[Pathomorphologists of berylliosis
Skin granulomas in systemic berylliosis are not distinguishable from granulomas in sarcoidosis, since they are almost not subjected to necrosis. Particles of beryllium, as a rule, are not visible in histological sections, but they are detected by spectrography.
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