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Beckonase

Medical expert of the article

Internist, infectious disease specialist
, medical expert
Last reviewed: 03.07.2025

Beconase is a pharmaceutical product used for seasonal allergies. Let's look at the features of the drug and the rules for its use.

The drug is a topical glucocorticosteroid in intranasal form. It has antiallergic, anti-inflammatory and anti-edematous properties. Suppression of inflammation is associated with the effect on cells through inhibition of receptors responsible in DNA for changing target genes that regulate the synthesis of protein molecules of the inflammatory process.

Active components block the formation of leukotrienes and inhibit the synthesis of genes regulating: COX, phospholipase A2, EDN1 of the allergic process. The antiallergic effect is based on the suppression of receptor sensitivity to biologically active substances and mechanical irritants that affect nonspecific nasal hyperreactivity, restores the sense of smell.

ATC classification

R01AD01 Beclometasone

Active ingredients

Беклометазон

Pharmacological group

Глюкокортикостероиды

Pharmachologic effect

Противоаллергические препараты

Indications Beckonase

Intranasal spray is used to treat and prevent pollinosis. It is prescribed for allergic rhinitis and vasomotor rhinitis. Indications for the use of Bekonase are related to the mechanism of action of its components. It is effective in the complex therapy of infectious and inflammatory diseases of the nasal passages and paranasal sinuses.

With special caution it is prescribed in combination with systemic steroids, as there is a risk of adrenal dysfunction. The use of the drug after recent surgical interventions in the nasal cavity, injuries or ulcers of the nasal mucosa is possible with appropriate medical supervision.

Despite the fact that Beconase relieves the symptoms of seasonal allergic rhinitis, particularly severe cases associated with an increased number of allergens require additional treatment. Additional therapy is also necessary for pathological symptoms from the visual organs.

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Release form

The hormonal drug is available as a nasal spray. Its active ingredient is beclomethasone dipropionate. Each dose contains 50 mcg of this substance. The drug is available in 100- and 180-dose vials. The vials are polypropylene with a dosing device, nasal adapter, and cap.

Pharmacodynamics

The drug is intended for local use. Its pharmacodynamics indicate a powerful anti-inflammatory and vasoconstrictive effect. The active component beclomethasone dipropionate is an analogue of GCS. In the process of metabolism, it is transformed into an active metabolite beclomethasone-17-monopropionate with a high local anti-inflammatory effect. Its regular use prevents allergy symptoms.

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Pharmacokinetics

After administration, it is rapidly absorbed from the nasal mucosa. Pharmacokinetics indicate that about 5% of the inhaled dose enters the systemic circulation and undergoes complete biotransformation during the first pass through the liver.

Bioavailability is low. Minimal absorption reduces the risk of adverse reactions with long-term use of Beconase. The half-life is 12-15 hours, about 15% is eliminated by the kidneys, 35-75% is excreted in feces as inactive metabolites.

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Dosing and administration

The medicine is intended for intranasal use. The method of administration and doses of Beconase depend on the severity of allergy symptoms and the individual characteristics of the patient's body. Therefore, before using it, it is better to consult with your doctor.

For the treatment of children over 6 years of age and adults, one dose (3-4 instillations) per day in each nostril is recommended. The maximum dosage is two doses-injections per day (400 mcg). A persistent therapeutic effect is observed 5-7 days after the first use.

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Use Beckonase during pregnancy

The intranasal spray has pronounced local activity and minimal systemic effects. The use of Beconase during pregnancy is possible with a high probability of benefit to the mother. The use of the spray during lactation is also permitted, since the accumulation of active components in breast milk is minimal.

Contraindications

Beconase has a number of contraindications for use, let's consider them:

  • Intolerance to the components of the product
  • Childhood age of patients
  • Severe attacks of bronchial asthma
  • Candidiasis
  • Tuberculosis

Using the spray in the presence of contraindications is dangerous, as it can cause uncontrolled reactions from many organs and systems.

Side effects Beckonase

Antiallergic spray can cause side effects. Beconase provokes such reactions:

  • From the immune system: rash, urticaria, itching, shortness of breath, bronchospasm, swelling, anaphylactic reactions.
  • From the visual organs: cataract, increased intraocular pressure, glaucoma.
  • From the nervous system: impaired taste sensitivity, presence of an unpleasant taste or smell.
  • From the respiratory system: irritation, dryness of the nose and throat, nosebleeds, cough, dyspnea, in rare cases, perforation of the nasal septum is observed.

Long-term use or use of high doses may cause candidiasis, osteoporosis, and decreased function of the adrenal cortex.

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Overdose

Increased doses of Beconase cause reversible suppression of the hypothalamic-pituitary-adrenal system. Overdose requires emergency care. There is no specific antidote, so you should consult a doctor and adjust the therapeutic doses of the drug. Restoration of the hypothalamic-pituitary-adrenal system function occurs within 36-48 hours.

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Interactions with other drugs

The active components of the spray may enhance their effect when used with other glucocorticosteroids or b-adrenoreceptors. To prevent unwanted side effects, any interaction with other drugs should be monitored by the attending physician.

Storage conditions

According to storage conditions, the pharmaceutical product must be kept out of reach of children, protected from sunlight and moisture. The bottle of the drug should be handled with special care, it must not be damaged. The recommended storage temperature should not exceed 30 °C.

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Shelf life

Beconase must be used within 36 months from the date of manufacture. The shelf life of an opened spray is 28 days. After this date, the drug must be disposed of. This is due to the risk of developing adverse reactions and loss of its medicinal effectiveness.

Manufacturer

Глаксо Веллком С.А. для "Омега Фарма Украина, ООО", Испания/Украина


Attention!

To simplify the perception of information, this instruction for use of the drug "Beckonase" translated and presented in a special form on the basis of the official instructions for medical use of the drug. Before use read the annotation that came directly to medicines.

Description provided for informational purposes and is not a guide to self-healing. The need for this drug, the purpose of the treatment regimen, methods and dose of the drug is determined solely by the attending physician. Self-medication is dangerous for your health.

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