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Adrenal antibodies in the blood.
Medical expert of the article
Last reviewed: 05.07.2025
Antibodies to the adrenal glands are directed against the microsomal structures of the adrenal cortex cells. They belong to IgG, are organ-specific and appear more often in women. Determination of antibodies in the blood serum is used to establish the pathogenetic mechanisms of the development of primary adrenal atrophy.
Antibodies are detected in 38-60% of patients with idiopathic Addison's disease. Over time, the concentration of antibodies in Addison's disease may change, and they may disappear. Antibodies to adrenal antigens can be detected in 7-18% of patients with tuberculous etiology of Addison's disease and 1% of elderly patients.
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