Extragenital diseases of the mother and premature termination of pregnancy

, medical expert
Last reviewed: 20.11.2021

All iLive content is medically reviewed or fact checked to ensure as much factual accuracy as possible.

We have strict sourcing guidelines and only link to reputable media sites, academic research institutions and, whenever possible, medically peer reviewed studies. Note that the numbers in parentheses ([1], [2], etc.) are clickable links to these studies.

If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please select it and press Ctrl + Enter.

Extragenital diseases of the mother are one of the frequent causes of premature termination of pregnancy. The group of high risk for miscarriage is primarily women with diseases of the cardiovascular system, hypertension, chronic kidney disease, liver, intestines.

With habitual miscarriages, diseases of an autoimmune nature are closely associated - systemic lupus erythematosus, in the first place.

Disorders in the hemostasis system, congenital and acquired, are associated not only with the loss of pregnancy, but also with high maternal mortality due to thrombophilic complications: antiphospholipid syndrome, hereditary hemostasis defects, hyperhomocystinemia, thrombocythemia, etc.

With unfavorable course of pregnancy and its unfavorable outcomes in terms of miscarriage and frequent abnormalities in the fetus, such maternal diseases as insulin-dependent diabetes, hypofunction and hyperthyroidism of the thyroid, phenylketonuria in the mother, severe forms of myasthenia gravis, multiple sclerosis, and significant obesity are associated.

Premature termination of pregnancy with extragenital pathology is facilitated by significant changes in the mother's body, metabolic disorders and complications of pregnancy that accompany extragenital pathology. Vascular disorders, hypoxia, often lead to the loss of pregnancy in the pathology of the mother, and often contributes to the pharmacotherapy of the underlying diseases of the mother (iatrogenic actions).

trusted-source[1], [2], [3], [4], [5]

Translation Disclaimer: The original language of this article is Russian. For the convenience of users of the iLive portal who do not speak Russian, this article has been translated into the current language, but has not yet been verified by a native speaker who has the necessary qualifications for this. In this regard, we warn you that the translation of this article may be incorrect, may contain lexical, syntactic and grammatical errors.

You are reporting a typo in the following text:
Simply click the "Send typo report" button to complete the report. You can also include a comment.