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D-dimer analysis in pregnancy
Medical expert of the article
Last reviewed: 05.07.2025
It is recommended not to ignore the D-dimer analysis during pregnancy.
D-dimer refers to the products of fibrin lysis, which is part of the thrombus. The analysis allows you to find out whether there is a risk of accelerated thrombus formation in the expectant mother or not. Before taking blood, it is advisable not to consume liquids and food for at least 12 hours.
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Normal D-dimer levels for pregnant women
- 1st trimester – 750 ng/ml.
- 2nd trimester – 1000 ng/ml.
- 3rd trimester – no more than 1500 ng/ml.
Increased D-dimer during pregnancy
An increase in the level indicates an increased risk of blood clots, and this can be preceded by a number of diseases:
- Presence of diabetes mellitus.
- Presence of diseases of the urinary system.
- Confirmation of gestosis.
- Confirmation of infectious diseases.
- Presence of liver disease.
- Early placental abruption and risk of miscarriage.
D-dimer below normal during pregnancy
If D-dimer is significantly lower than the norm for pregnant women, this already indicates a decrease in blood clotting and the risk of bleeding incompatible with life. In such cases, hospitalization, consultation with a hematologist and a course of coagulants are required. It is especially important to conduct a D-dimer test immediately before childbirth, when the fact of blood loss is irrefutable and in case of complications, it will be necessary to provide quick assistance.